{"id":"W1512151374","doi":"10.1002/9781118105771.ch10","title":"Irreversible Inhibitors of Tissue Transglutaminase","year":2011,"lang":"en","type":"review","venue":"Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects","topic":"Blood properties and coagulation","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Tissue transglutaminase; Chemistry; Biochemistry; Enzyme; Substrate specificity; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006471766,0.0007493456,0.003200707,0.001084088,0.00008412539,0.00000263416,0.0002710873,0.003259413,0.00006602745],"category_scores_gemma":[0.0002547598,0.0005896564,0.0002961493,0.0009149827,0.002473378,0.0002491761,0.000159565,0.001748581,0.000005024571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005372761,"about_ca_system_score_gemma":0.0002125241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005185227,"about_ca_topic_score_gemma":0.00004620624,"domain_scores_codex":[0.9953519,0.0009126097,0.001884444,0.001072548,0.0001130456,0.0006655233],"domain_scores_gemma":[0.9978535,0.0004407497,0.0009620499,0.000492321,0.0001043844,0.0001470376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001083027,0.0007647111,0.005527935,0.01379347,0.0009771315,0.00165624,0.0009726049,0.0001067691,0.0005923872,0.01749666,0.000006159945,0.9570229],"study_design_scores_gemma":[0.02752989,0.0172077,0.001914644,0.07805288,0.01122672,0.02903088,0.00130365,0.0000958065,0.01575125,0.169773,0.6424959,0.00561773],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0203326,0.9740802,0.00004181933,0.00005603313,0.0008806853,0.001130262,0.00002359324,0.00003915573,0.00341564],"genre_scores_gemma":[0.1455327,0.853598,0.0003853463,0.00003331091,0.00001814346,0.0000625889,0.000165291,0.00005501778,0.0001495655],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9514052,"threshold_uncertainty_score":0.9996555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00989077905701709,"score_gpt":0.2965255475943686,"score_spread":0.2866347685373515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}