{"id":"W1512591645","doi":"10.1002/bies.201400032","title":"Variable escape from X‐chromosome inactivation: Identifying factors that tip the scales towards expression","year":2014,"lang":"en","type":"review","venue":"BioEssays","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"X-inactivation; Biology; Genetics; Allele; X chromosome; Gene; Heterochromatin; Chromosome; XIST; Skewed X-inactivation; Population; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005674792,0.0008520408,0.001434003,0.002811356,0.00024053,0.0009722729,0.0008436317,0.001145202,0.002882794],"category_scores_gemma":[0.0006165043,0.0003247821,0.0003340846,0.002347002,0.0007332881,0.001604889,0.0006976061,0.001465441,0.002510774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000610503,"about_ca_system_score_gemma":0.0008171406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009691858,"about_ca_topic_score_gemma":0.001701365,"domain_scores_codex":[0.9998415,0.00002127344,0.00002697349,0.00003412082,0.00006206924,0.00001414451],"domain_scores_gemma":[0.9997324,0.0001178145,0.00004177468,0.000008260433,0.000070783,0.00002891507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006609641,0.00003647028,0.0002790238,0.01225513,0.00005416289,0.0002197261,0.0000537744,0.000239869,0.001909553,0.003312599,0.01582033,0.9657533],"study_design_scores_gemma":[0.00001051132,0.00007232594,0.001099575,0.001929408,0.00006727653,0.001691857,0.00007279844,0.0000550756,0.00063196,0.001747141,0.9926031,0.00001892433],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009486622,0.9988835,0.0001072557,0.0001724617,0.00009841092,0.000002571594,0.00001347437,0.000005560225,0.0006217872],"genre_scores_gemma":[0.0004454173,0.9987734,0.0001320747,0.0001237618,0.00006984286,0.000003581219,0.00002191726,0.000001305911,0.0004287701],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002882794,"threshold_uncertainty_score":0.009643972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0600277012669772,"score_gpt":0.3238006211276913,"score_spread":0.2637729198607141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}