{"id":"W151327469","doi":"10.1016/j.ajpath.2014.01.008","title":"CD133-Targeted Niche-Dependent Therapy in Cancer","year":2014,"lang":"en","type":"review","venue":"American Journal Of Pathology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Mach-Gaensslen Foundation of Canada; American Society for Investigative Pathology; Brigham and Women's Hospital","keywords":"Cancer stem cell; Niche; Context (archaeology); Biology; Cancer; Ecological niche; Cancer therapy; Cancer research; Ecology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000798677,0.0003529743,0.004079865,0.0005703192,0.00001760499,0.000007651225,0.0002512662,0.0001566866,0.0003517311],"category_scores_gemma":[0.00008045258,0.0002385012,0.0007662103,0.0004634604,0.0002469276,0.000026345,0.00003519552,0.001027032,0.00002078176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002896976,"about_ca_system_score_gemma":0.001009524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001557997,"about_ca_topic_score_gemma":0.00004580755,"domain_scores_codex":[0.9973131,0.0005493166,0.001189223,0.0002909381,0.0002841873,0.0003732531],"domain_scores_gemma":[0.9972643,0.0001522178,0.001877882,0.0003409996,0.0001571019,0.000207475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001062124,0.0001205539,0.0001714967,0.0007729253,0.0002425837,0.001596635,0.00009932633,0.000001423263,0.00003353414,0.000004533172,0.0004356763,0.9964151],"study_design_scores_gemma":[0.001127181,0.002280577,0.0001254594,0.003410608,0.0007835975,0.005467994,0.00006210271,2.855708e-7,0.00001422789,0.000009953954,0.9865122,0.0002058503],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001600247,0.9968293,0.0000802153,0.0002174744,0.0007069917,0.0002896077,0.00002088596,0.000007379157,0.0002478817],"genre_scores_gemma":[0.0007242995,0.9968235,0.0006402246,0.0007583668,0.0007414047,0.0000321332,0.000007734764,0.00006932226,0.000202938],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9962093,"threshold_uncertainty_score":0.9725796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04753252077419125,"score_gpt":0.3931447351134999,"score_spread":0.3456122143393087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}