{"id":"W1513466924","doi":"10.1111/j.1751-1097.2011.00942.x","title":"Calculation of Singlet Oxygen Dose Using Explicit and Implicit Dose Metrics During Benzoporphyrin Derivative Monoacid Ring A (BPD‐MA)‐PDT <i>In Vitro</i> and Correlation with MLL Cell Survival","year":2011,"lang":"en","type":"article","venue":"Photochemistry and Photobiology","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre; Juravinski Cancer Centre","funders":"National Cancer Institute","keywords":"Singlet oxygen; Photobleaching; Photodynamic therapy; Photochemistry; Oxygen; Chemistry; Intracellular; Radiosensitivity; Fluorescence; Rose bengal; Biophysics; Irradiation; Biology; Biochemistry; Optics; Physics; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004878546,0.0003760277,0.0003344548,0.0002922659,0.00008739909,0.00041579,0.0003266403,0.0004781648,0.0002689858],"category_scores_gemma":[0.001270429,0.0001786448,0.000211237,0.0002311705,0.0002610121,0.000354298,0.0002710528,0.0004891987,0.0001243637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005076673,"about_ca_system_score_gemma":0.0001707668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007026627,"about_ca_topic_score_gemma":0.0006817933,"domain_scores_codex":[0.9997265,0.00004985532,0.00001848047,0.00004606767,0.0001411645,0.00001795182],"domain_scores_gemma":[0.9995177,0.000177877,0.0001494679,0.0000417442,0.00008962847,0.00002365325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003347154,0.00005543861,0.004318698,0.0001113266,0.00001708352,0.00004062487,0.00007618594,0.01148962,0.9674598,0.0002281853,0.00003386025,0.01583448],"study_design_scores_gemma":[0.000006616605,0.0002793022,0.007076348,0.000004342422,0.00001487252,0.0000781213,0.0000153226,0.06894693,0.9231094,0.0001090949,0.0003435895,0.00001608999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9208009,0.0006499777,0.07764483,0.00002703153,0.000008523892,0.00004402614,0.0001234146,0.0002957209,0.0004054863],"genre_scores_gemma":[0.9716381,0.0002996122,0.02742286,0.000009574132,0.000002108653,0.00004163448,0.0001570295,0.00002743785,0.0004015549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007026627,"threshold_uncertainty_score":0.003683388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03083742469610034,"score_gpt":0.2736012804714344,"score_spread":0.2427638557753341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}