{"id":"W1514874279","doi":"10.1186/ar1379","title":"Complement and autoimmunity: new insights into old questions","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Innate immune system; Acquired immune system; Complement system; Immunology; Complement receptor; Alternative complement pathway; Classical complement pathway; Arthritis; Immune system; Complement factor B; Inflammation; Biology; Autoimmunity","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008750454,0.001348105,0.002484468,0.005592104,0.001313718,0.00700115,0.002330958,0.006626429,0.01066708],"category_scores_gemma":[0.01517647,0.0005324036,0.0009175224,0.003134568,0.01338234,0.01692757,0.003444856,0.009947039,0.001468927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002953976,"about_ca_system_score_gemma":0.002573857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001988499,"about_ca_topic_score_gemma":0.00206345,"domain_scores_codex":[0.9956786,0.00235716,0.0003691165,0.0005292965,0.0007717765,0.0002941187],"domain_scores_gemma":[0.9673534,0.0270885,0.001071556,0.001065258,0.002344084,0.001077305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004411457,0.0001800733,0.00547774,0.005485733,0.0002574421,0.001589935,0.003327586,0.0006451939,0.0006905081,0.2484705,0.151399,0.5820352],"study_design_scores_gemma":[0.00003917253,0.0001675358,0.004135903,0.01115577,0.00008210283,0.004251029,0.004101757,0.0005741108,0.0001576126,0.4213685,0.5538794,0.00008725186],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001311928,0.8801879,0.002905645,0.1042849,0.006269562,0.00002117146,0.0001326507,0.000035204,0.004850969],"genre_scores_gemma":[0.03857353,0.864357,0.005362084,0.04090029,0.04682223,0.0001019901,0.0001787384,0.00004294133,0.00366119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01066708,"threshold_uncertainty_score":0.0462774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0844653131574409,"score_gpt":0.4073993845243599,"score_spread":0.322934071366919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}