{"id":"W1514874279","doi":"10.1186/ar1379","title":"Complement and autoimmunity: new insights into old questions","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Innate immune system; Acquired immune system; Complement system; Immunology; Complement receptor; Alternative complement pathway; Classical complement pathway; Arthritis; Immune system; Complement factor B; Inflammation; Biology; Autoimmunity","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005300574,0.0001277785,0.00024548,0.0003455619,0.0006291186,0.00008516692,0.0001514546,0.00007356415,0.0005109596],"category_scores_gemma":[0.0002158916,0.0001090232,0.00005574899,0.0004643069,0.000532842,0.0001169189,0.0003522824,0.0007699738,0.0004547295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001270263,"about_ca_system_score_gemma":0.0005240445,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0170953,"about_ca_topic_score_gemma":0.002736978,"domain_scores_codex":[0.9977671,0.0001532298,0.0002471718,0.0003084693,0.0009643525,0.0005596939],"domain_scores_gemma":[0.9986001,0.0001779288,0.0000163237,0.0003384829,0.0002967751,0.0005703759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006105753,0.000940959,0.01393037,0.0002890109,0.0002041451,0.00145423,0.007659656,0.00001287538,0.04089747,0.3312647,0.01823728,0.5844987],"study_design_scores_gemma":[0.005522646,0.002350527,0.1328373,0.001046339,0.00001035889,0.000433322,0.0007837221,0.00009747297,0.006674682,0.101036,0.7489089,0.0002987139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9447278,0.01411319,0.0000983898,0.02971846,0.00005712701,0.0005874793,0.000006277854,0.00006177191,0.01062955],"genre_scores_gemma":[0.9748006,0.01360008,0.002495438,0.0004134525,0.0002378333,0.00003783714,0.00004898779,0.00002057813,0.008345175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7306716,"threshold_uncertainty_score":0.9894499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0844653131574409,"score_gpt":0.4073993845243599,"score_spread":0.322934071366919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}