{"id":"W1514971676","doi":"10.1002/0470092645.ch8","title":"Role of Subunit Assembly in Autosomal Dominant Retinitis Pigmentosa Linked to Mutations in Peripherin 2","year":2003,"lang":"en","type":"article","venue":"Novartis Foundation symposium","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute","keywords":"Peripherin; Retinitis pigmentosa; Retinal degeneration; Mutant; Biology; Cell biology; Protein subunit; Xenopus; Mutation; Chemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002677071,0.0001203564,0.0001507633,0.0001398024,0.00003535049,0.00002064705,0.00008399815,0.0001236884,0.0001240587],"category_scores_gemma":[0.0000475512,0.0001406139,0.00005153456,0.0003209398,0.00003437797,0.0000126573,0.00001540459,0.00007334537,0.00002084578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003855227,"about_ca_system_score_gemma":0.0001020547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001458313,"about_ca_topic_score_gemma":0.001511831,"domain_scores_codex":[0.9988852,0.00008642175,0.0004113791,0.0002736776,0.0001407506,0.000202549],"domain_scores_gemma":[0.9995568,0.000009518191,0.00008235405,0.000206638,0.00008795803,0.00005676484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007051729,0.0001117025,0.03060786,0.00001082589,0.000006872578,0.000003473344,0.0006371982,0.0003071724,0.9669357,0.0007891138,0.000002902789,0.0005166453],"study_design_scores_gemma":[0.001895101,0.0004166669,0.1863918,0.00005478473,0.00001783661,0.00001519387,0.0006207434,0.0004293318,0.7563412,0.0002149794,0.05325027,0.0003520167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901158,0.00004449171,0.005727687,0.0001708459,0.000100835,0.0003066435,0.000007418963,0.000006581843,0.003519737],"genre_scores_gemma":[0.9975072,0.00003723429,0.0008775186,0.00004880999,0.00003061648,0.00005753526,0.001112347,0.00001718755,0.0003116036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2105945,"threshold_uncertainty_score":0.5734068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009719606167511243,"score_gpt":0.2449686779585608,"score_spread":0.2352490717910495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}