{"id":"W1515050147","doi":"10.1002/dvdy.23954","title":"Expression of ski can act as a negative feedback mechanism on retinoic acid signaling","year":2013,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Forskningsrådet om Hälsa, Arbetsliv och Välfärd","keywords":"Retinoic acid; Retinoic acid-inducible orphan G protein-coupled receptor; Biology; Retinoic acid receptor beta; Retinoic acid receptor gamma; Cell biology; Signal transduction; Tretinoin; Retinoic acid receptor; Retinoic acid receptor alpha; Psychological repression; Retinoid X receptor gamma; Gene expression; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007353309,0.0002179332,0.0001654633,0.00005790183,0.00009658697,0.0000295657,0.0002465424,0.0001506152,0.0001452923],"category_scores_gemma":[0.0001132162,0.0002086447,0.00007321385,0.00008535413,0.00006688295,0.000006564615,0.0001722275,0.00009683203,0.00006129373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009560007,"about_ca_system_score_gemma":0.0001981698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005566457,"about_ca_topic_score_gemma":0.00003534803,"domain_scores_codex":[0.9988396,0.00005003662,0.0002761194,0.0003524022,0.0002279786,0.0002538338],"domain_scores_gemma":[0.9994123,0.0000224573,0.0001508676,0.0001986106,0.00009603479,0.0001197421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007508058,0.00009149391,0.001309024,0.00002635008,0.00004022203,0.000003203368,0.0002360688,0.00005523004,0.9963238,0.0001363753,0.0001881112,0.001515095],"study_design_scores_gemma":[0.0004026192,0.0001633463,0.002397121,0.0001138297,0.000008588285,0.000007136382,0.0005386894,0.0002073311,0.9951359,0.0006783265,0.00008385989,0.0002632566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977292,0.00003668753,0.0005852714,0.00003447353,0.000101862,0.0002785982,0.00004285987,0.00002221021,0.001168823],"genre_scores_gemma":[0.9894453,0.000008754168,0.009340565,0.0002288278,0.00004159844,0.00004974032,0.0004017352,0.00003743839,0.0004460117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008755294,"threshold_uncertainty_score":0.8508285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005842511425338863,"score_gpt":0.2164274265640035,"score_spread":0.2105849151386646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}