{"id":"W1515810516","doi":"10.1111/j.1399-0004.2004.00310.x","title":"The dynamics of X‐inactivation skewing as women age","year":2004,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; BC Research (Canada); University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Skewed X-inactivation; X-inactivation; DNA methylation; Epigenetics; X chromosome; Biology; Young adult; Senescence; Allele; Methylation; Physiology; Pregnancy; Etiology; Locus (genetics); Genetics; Internal medicine; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004045054,0.0001141157,0.0001622503,0.00002723777,0.0001214052,0.00003062212,0.0002925943,0.0001752893,0.00001272499],"category_scores_gemma":[0.0004218066,0.00008638462,0.0001352011,0.000116362,0.0003914989,0.000002141393,0.0001771332,0.0001313806,0.00001101659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001806961,"about_ca_system_score_gemma":0.000107825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007371413,"about_ca_topic_score_gemma":0.00003380256,"domain_scores_codex":[0.9987299,0.00006370892,0.0005919605,0.0002315347,0.0001591024,0.0002237821],"domain_scores_gemma":[0.9991342,0.00009134692,0.0001826725,0.0003545997,0.0001251108,0.0001120881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002071462,0.003942277,0.08700198,0.0002822418,0.001181939,0.00008315697,0.002364016,0.007546284,0.1554245,0.1588677,0.0009191773,0.5803152],"study_design_scores_gemma":[0.008214187,0.01248839,0.2673951,0.0001335252,0.000139849,0.00005292994,0.01072063,0.000886033,0.4164888,0.2071563,0.07477915,0.001545202],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950321,0.0002508434,0.0009200209,0.0006531763,0.0002518006,0.0001141354,0.000005171789,0.000009259005,0.002763481],"genre_scores_gemma":[0.9958049,0.001594232,0.0008825778,0.0004199847,0.000213244,0.00001261678,0.00002500153,0.00001304752,0.001034395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.57877,"threshold_uncertainty_score":0.3522663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01845774065854234,"score_gpt":0.31649999153347,"score_spread":0.2980422508749276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}