{"id":"W1516980941","doi":"10.1002/cncr.28358","title":"Randomized phase 2 study of pegylated SN‐38 (EZN‐2208) or irinotecan plus cetuximab in patients with advanced colorectal cancer","year":2013,"lang":"en","type":"article","venue":"Cancer","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute","keywords":"Medicine; Irinotecan; Cetuximab; Colorectal cancer; Internal medicine; Cancer; Randomized controlled trial; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001771186,0.002277806,0.003457039,0.0005738878,0.0004306987,0.001195534,0.001145513,0.002121025,0.01008997],"category_scores_gemma":[0.001470256,0.001145972,0.001246194,0.0004927008,0.00149469,0.001384753,0.0005434062,0.003518652,0.001511887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001263532,"about_ca_system_score_gemma":0.002770381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180689,"about_ca_topic_score_gemma":0.003190165,"domain_scores_codex":[0.9993209,0.0003170593,0.00002878982,0.0001535151,0.0000531273,0.0001266174],"domain_scores_gemma":[0.9991067,0.0001677192,0.0001434472,0.00007571414,0.00005762896,0.0004487699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9688725,0.01465002,0.0004871866,0.0002209995,0.0003016111,0.0000442581,0.00004036851,0.0004982091,0.003422667,0.0001070956,0.0009560872,0.01039893],"study_design_scores_gemma":[0.9209818,0.0763749,0.0008065688,0.000009741536,0.0001281063,0.00003242933,0.0000114511,0.0003987343,0.0003650351,0.000132832,0.0007469847,0.00001138321],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790324,0.002172632,0.0008858566,0.001118211,0.0007549825,0.01053925,0.001713818,0.0002253706,0.003557381],"genre_scores_gemma":[0.9643423,0.002140125,0.003078856,0.002754536,0.0006615187,0.01563904,0.002619924,0.00006604952,0.008697764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01008997,"threshold_uncertainty_score":0.03375429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032666784852949,"score_gpt":0.2872047949454441,"score_spread":0.2768781270969146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}