{"id":"W1516980941","doi":"10.1002/cncr.28358","title":"Randomized phase 2 study of pegylated SN‐38 (EZN‐2208) or irinotecan plus cetuximab in patients with advanced colorectal cancer","year":2013,"lang":"en","type":"article","venue":"Cancer","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute","keywords":"Medicine; Irinotecan; Cetuximab; Colorectal cancer; Internal medicine; Cancer; Randomized controlled trial; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001020456,0.0002431769,0.0005475631,0.00006795614,0.00004122079,0.00001269649,0.000182192,0.0001109818,0.0003967505],"category_scores_gemma":[0.00001792279,0.0001741951,0.00007078232,0.0001979005,0.00007628098,0.000009958284,0.00006457759,0.0001127382,0.000001795519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001146602,"about_ca_system_score_gemma":0.0002937076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001382304,"about_ca_topic_score_gemma":0.002053193,"domain_scores_codex":[0.9986249,0.00008701615,0.0003537683,0.0004132288,0.0002009752,0.0003201336],"domain_scores_gemma":[0.9992045,0.00001640691,0.0001647187,0.0002673999,0.0002562733,0.00009077342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5199447,0.005312204,0.008982355,0.0001292349,0.001444983,0.000008843381,0.002988474,0.002945097,0.3847835,0.00002930947,0.0003272099,0.07310408],"study_design_scores_gemma":[0.7742758,0.006625514,0.005439315,0.0001122013,0.0001828589,9.347916e-7,0.0005914376,0.0005023394,0.2100248,0.00003295825,0.001576941,0.000634981],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963626,0.0007571355,0.00007917416,0.00004415854,0.0002608219,0.002316311,0.00006729155,0.0000117472,0.0001007856],"genre_scores_gemma":[0.9974456,0.0004254867,0.00006202943,0.0001379319,0.00006984652,0.001511032,0.00004873263,0.00004359642,0.0002557207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2543311,"threshold_uncertainty_score":0.7103471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032666784852949,"score_gpt":0.2872047949454441,"score_spread":0.2768781270969146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}