{"id":"W1517606468","doi":"10.1371/journal.ppat.1005050","title":"Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institute of Allergy and Infectious Diseases; European Commission; McKnight Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Simian immunodeficiency virus; Virology; Biology; Transduction (biophysics); Infectivity; Virus; Peripheral blood mononuclear cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002138017,0.0001901411,0.0002961326,0.0001679407,0.0001264144,0.00001808348,0.0002700938,0.0001668436,0.00007269471],"category_scores_gemma":[0.0001059405,0.0001297354,0.000103573,0.0003093518,0.0001315465,0.00008504042,0.0001569941,0.0003048682,0.0004869756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007904722,"about_ca_system_score_gemma":0.0001214868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002094369,"about_ca_topic_score_gemma":0.0003251222,"domain_scores_codex":[0.9985327,0.0004054338,0.00022443,0.0003327241,0.0001191298,0.0003855596],"domain_scores_gemma":[0.9991634,0.00009817003,0.0001089965,0.000476389,0.00009717434,0.00005582316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000156015,0.0009744737,0.02801217,0.000008780181,0.00008894642,0.00002656051,0.002284791,0.00000153319,0.9654715,0.00002508254,0.001919819,0.001030313],"study_design_scores_gemma":[0.001511771,0.0003718696,0.02929996,0.00005478353,0.0000411817,0.000003396962,0.0002534163,0.00000172323,0.9667718,0.00001520753,0.00155403,0.000120901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973593,0.0002578758,0.00002236466,0.0001800579,0.0001322826,0.0006900102,0.000609475,0.00002651366,0.0007221698],"genre_scores_gemma":[0.9988083,0.00005219489,0.00008453761,0.00008305415,0.00002773212,0.00005631468,0.00004536818,0.00001750454,0.0008249521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002031375,"threshold_uncertainty_score":0.6259249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07422111363643767,"score_gpt":0.2896933506865096,"score_spread":0.2154722370500719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}