{"id":"W1518200090","doi":"10.1593/neo.08174","title":"Decitabine-Induced Demethylation of 5′ CpG Island in GADD45A Leads to Apoptosis in Osteosarcoma Cells","year":2008,"lang":"en","type":"article","venue":"Neoplasia","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Hospital for Sick Children; Princess Margaret Cancer Centre; BC Cancer Agency; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Decitabine; Apoptosis; Cancer research; Carcinogenesis; DNA methylation; Biology; Molecular biology; Cancer; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000874738,0.0001811796,0.0002627148,0.0001564185,0.0001454578,0.0001789856,0.0001305925,0.0001278171,0.0007975404],"category_scores_gemma":[0.00009030485,0.0001368377,0.0001599572,0.0001408158,0.0001369838,0.00007176295,0.0001433647,0.0003373657,0.0002192726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003075765,"about_ca_system_score_gemma":0.0001577482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001033068,"about_ca_topic_score_gemma":0.002132608,"domain_scores_codex":[0.9999158,0.00001001646,0.00001084937,0.0000189621,0.00002322572,0.00002106758],"domain_scores_gemma":[0.9999338,0.00001264543,0.00001867312,0.00001518698,0.000006243997,0.00001341155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006519345,0.00001616588,0.0001306697,0.00001409138,0.000003400119,0.0000260617,0.00001124544,0.00003633829,0.9988845,0.00004119305,0.00001382206,0.0007572991],"study_design_scores_gemma":[0.00001025434,0.0001202552,0.002423648,0.000001904283,0.000006477979,0.0001153,0.00001429631,0.0003742867,0.9959615,0.00002647237,0.0009445327,0.000001173133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965944,0.001018793,0.001308171,0.00005491531,0.00001934468,0.00001476284,0.0001676741,0.00004581568,0.0007759936],"genre_scores_gemma":[0.9963313,0.000444336,0.0009829995,0.00003247289,0.000002413315,0.0000170265,0.0003278392,0.00001205574,0.001849638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001033068,"threshold_uncertainty_score":0.002668023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516546368217994,"score_gpt":0.2547028265736555,"score_spread":0.2395373628914756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}