{"id":"W151857649","doi":"10.1007/978-3-0348-0157-7_1","title":"Proteolytic Enzymes and Cell Signaling: Pharmacological Lessons","year":2011,"lang":"en","type":"book-chapter","venue":"","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Signal transduction; Receptor; Cell biology; Thrombin; Biology; Protease-activated receptor; Cell signaling; G protein-coupled receptor; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005019701,0.0009063619,0.0006981522,0.0008338101,0.0003319428,0.002187418,0.001117474,0.001602577,0.003931656],"category_scores_gemma":[0.0003271773,0.0003924088,0.0003035644,0.0007463892,0.001687878,0.003206177,0.0007298819,0.003903112,0.00346304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008544429,"about_ca_system_score_gemma":0.0005383265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003207836,"about_ca_topic_score_gemma":0.0009088819,"domain_scores_codex":[0.9998789,0.00001352492,0.00000742372,0.00002686375,0.00005535199,0.00001804068],"domain_scores_gemma":[0.9998791,0.00006796567,0.000006003675,0.00001023424,0.00001939378,0.00001728535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003094371,0.0002812574,0.0001384651,0.001719329,0.00003725982,0.0005594239,0.0002963714,0.0008934037,0.03348536,0.2513422,0.1243511,0.5865864],"study_design_scores_gemma":[0.00004918954,0.00007185411,0.0002436735,0.0002600871,0.0000188215,0.001008734,0.00008306045,0.0003492571,0.008542067,0.09815041,0.8911997,0.00002314612],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002664689,0.8630546,0.01653662,0.01345586,0.004027199,0.00002278268,0.0001072104,0.0002031662,0.09992787],"genre_scores_gemma":[0.02970146,0.8232812,0.01335647,0.008708003,0.004842052,0.0001100968,0.0002033887,0.00009828532,0.1196991],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003931656,"threshold_uncertainty_score":0.01315266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03165426787690866,"score_gpt":0.2482483387185514,"score_spread":0.2165940708416427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}