{"id":"W1518683511","doi":"10.1046/j.1432-1327.2000.01080.x","title":"Transforming growth factor β induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene‐1 in rat insulinoma cells","year":2000,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Homeobox; Insulinoma; Transcription factor; Endocrinology; Insulin; Internal medicine; Reporter gene; Transforming growth factor; Biology; Electrophoretic mobility shift assay; Promoter; Molecular biology; Gene expression; Chemistry; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001795884,0.0003602112,0.0001825122,0.0004056656,0.0001432489,0.000312184,0.0001514701,0.0001294722,0.001153462],"category_scores_gemma":[0.0001357097,0.0002535695,0.0002977492,0.0002254419,0.0001914888,0.0001413408,0.0001992863,0.0006007975,0.0005999314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002273854,"about_ca_system_score_gemma":0.0001830726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004828117,"about_ca_topic_score_gemma":0.0006424332,"domain_scores_codex":[0.9998673,0.000012145,0.00001295964,0.00002674756,0.00004671566,0.00003403493],"domain_scores_gemma":[0.9998567,0.00003375425,0.00003466508,0.00001866122,0.00001808295,0.00003810811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000102364,0.00001692199,0.0001549746,0.00001486882,0.000001856931,0.00003144021,0.00001172413,0.00001185717,0.9991185,0.0000373423,0.000007833428,0.0004904014],"study_design_scores_gemma":[0.00005366711,0.0003437565,0.006327929,0.00001026561,0.00001568474,0.0002340761,0.00004633043,0.0004198473,0.990743,0.00006701662,0.001733623,0.000004821461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992645,0.001411558,0.003821119,0.00008450296,0.0000447651,0.000028223,0.0003586916,0.00007761294,0.001528522],"genre_scores_gemma":[0.988765,0.001681747,0.004928163,0.0000501127,0.00001775346,0.00004836903,0.001016904,0.00003513138,0.003456726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001153462,"threshold_uncertainty_score":0.003858745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009639198447379262,"score_gpt":0.2059476146561104,"score_spread":0.1963084162087312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}