{"id":"W1519329230","doi":"10.1111/tra.12003","title":"Rab7 and Arl8 <scp>GTPases</scp> are Necessary for Lysosome Tubulation in Macrophages","year":2012,"lang":"en","type":"article","venue":"Traffic","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Cell biology; Lysosome; Biology; Endosome; Phagosome; Endocytic cycle; Rab; Microtubule; Motor protein; Dynein; GTPase; Endocytosis; Phagocytosis; Biochemistry; Cell; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001746049,0.0002476457,0.0002312655,0.0003083081,0.0003420064,0.0003771905,0.0002504065,0.0003800452,0.000942325],"category_scores_gemma":[0.0001992242,0.0002193226,0.0002262764,0.0001402384,0.0003006817,0.0002178041,0.0003555474,0.000488898,0.0009407068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005048547,"about_ca_system_score_gemma":0.0004049666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008466948,"about_ca_topic_score_gemma":0.0009644332,"domain_scores_codex":[0.9997855,0.00003994287,0.00002289812,0.00003292304,0.00006378574,0.0000549803],"domain_scores_gemma":[0.9997532,0.0000434252,0.00006251553,0.00003453584,0.00003496528,0.00007132195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008610791,0.00001594031,0.0003815326,0.00002698888,0.00000308154,0.0001090892,0.00001416342,0.00004568031,0.9984218,0.0001526604,0.00007660539,0.0006663841],"study_design_scores_gemma":[0.00002736358,0.0001141204,0.01684345,0.00001131242,0.00001654424,0.0007828239,0.00008954076,0.002207841,0.974291,0.0002120931,0.00539559,0.000008452261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994954,0.001762496,0.001652126,0.000228125,0.00001729188,0.00001231768,0.0002925593,0.0001500353,0.0009309617],"genre_scores_gemma":[0.9952603,0.0006239525,0.001334135,0.00006122918,0.00001204808,0.00004913869,0.0007269665,0.00005151262,0.001880718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000942325,"threshold_uncertainty_score":0.003662944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148445085831745,"score_gpt":0.2327686260393118,"score_spread":0.2212841751809943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}