{"id":"W1519480055","doi":"10.1046/j.1365-2125.2003.01892.x","title":"Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications","year":2003,"lang":"en","type":"review","venue":"British Journal of Clinical Pharmacology","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":1218,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Mucociliary clearance; Drug; Respiratory tract; Lung; Aerosolization; Drug delivery; Pharmacology; Intensive care medicine; Respiratory system; Inhalation; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1432967315851301,"score_gpt":0.4632112318442296,"score_spread":0.3199145002590995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["nonrandomized_trial","observational","not_applicable"],"consensus_intersection":[],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.0029449912260624093,"metaepi_narrow":0.0003509575036240177,"metaepi_broad":0.0020752269779507134,"bibliometrics":0.000045777065690089265,"sts":0.000045777065690089265,"scholarly_communication":0.00009155413138017853,"open_science":0.000015259021896696422,"research_integrity":0.0005645838101777677,"randomized_trial":0.00016784924086366064,"nonrandomized_trial":0.003250171663996338,"observational":0.0002136263065537499,"systematic_review":0.0046082246128023195,"meta_analysis":0.001007095445181964,"case_report":0.0006561379415579462,"qualitative":0.000015259021896696422,"simulation_or_modeling":0.000289921416037232,"bench_or_experimental":0.01637293049515526,"theoretical_or_conceptual":0.00009155413138017853,"not_applicable":0.0034790569924467844,"design_other":0.0660868238345922},"gemma":{"metaresearch":0.0014190890363927672,"metaepi_narrow":0.00007629510948348211,"metaepi_broad":0.0010223544670786603,"bibliometrics":0.00010681315327687495,"sts":0.000015259021896696422,"scholarly_communication":0.000015259021896696422,"open_science":0.000015259021896696422,"research_integrity":0.0002746623941405356,"randomized_trial":0.00019836728465705348,"nonrandomized_trial":0.00022888532845044633,"observational":0.06555275806820783,"systematic_review":0.021316853589684902,"meta_analysis":0.0006256198977645533,"case_report":0.0005340657663843748,"qualitative":0.000030518043793392844,"simulation_or_modeling":0.000045777065690089265,"bench_or_experimental":0.0004272526131074998,"theoretical_or_conceptual":0.000015259021896696422,"not_applicable":0.3989013504234379}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}