{"id":"W1519592050","doi":"10.1038/npre.2007.1248.1","title":"Internal ribosomal entry site lacks secondary structure","year":2007,"lang":"en","type":"preprint","venue":"Nature Precedings","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Internal ribosome entry site; Protein secondary structure; Ribosome; Translation (biology); Messenger RNA; Biology; Eukaryotic translation; Eukaryotic initiation factor; Nucleic acid secondary structure; Computational biology; RNA; Nucleic acid structure; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002045393,0.0003599463,0.0004280079,0.0003034191,0.0002199672,0.0005876754,0.0001597842,0.0002822727,0.002257698],"category_scores_gemma":[0.0004929425,0.0001015846,0.0002297143,0.0001854537,0.0002598852,0.0001711087,0.0002589876,0.0004247358,0.002180155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002298172,"about_ca_system_score_gemma":0.0003129778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002538895,"about_ca_topic_score_gemma":0.0002012834,"domain_scores_codex":[0.9997733,0.00002297183,0.0000207715,0.00006565583,0.00007530335,0.00004200634],"domain_scores_gemma":[0.9993461,0.000115455,0.0001690205,0.0001322273,0.0001475763,0.00008962667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001443439,0.00003405056,0.002917364,0.00006834274,0.00001116641,0.0002690054,0.00002858311,0.0001968598,0.9896811,0.002542563,0.0002398188,0.003866787],"study_design_scores_gemma":[0.00006594543,0.0007948467,0.02631333,0.00002946437,0.00006264601,0.004387807,0.00009935409,0.002560728,0.9369985,0.007394104,0.02127573,0.00001756425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784204,0.002384803,0.01019415,0.0001866571,0.0001158946,0.00002782749,0.001090473,0.000336777,0.007242952],"genre_scores_gemma":[0.991067,0.0003038979,0.002641877,0.00006687169,0.00003176534,0.0000126144,0.003196659,0.00002330313,0.002655982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002257698,"threshold_uncertainty_score":0.007552803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004814477618248917,"score_gpt":0.2521950281545075,"score_spread":0.2473805505362586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}