{"id":"W1519592050","doi":"10.1038/npre.2007.1248.1","title":"Internal ribosomal entry site lacks secondary structure","year":2007,"lang":"en","type":"preprint","venue":"Nature Precedings","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Internal ribosome entry site; Protein secondary structure; Ribosome; Translation (biology); Messenger RNA; Biology; Eukaryotic translation; Eukaryotic initiation factor; Nucleic acid secondary structure; Computational biology; RNA; Nucleic acid structure; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0003432935,0.0005762954,0.0004124686,0.0001370186,0.00009499182,0.00013207,0.0008120349,0.004074776,0.0004814777],"category_scores_gemma":[0.0001921537,0.000547937,0.0003382759,0.00007299729,0.00007773955,0.00000625516,0.001377211,0.002997579,0.00002092434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005094102,"about_ca_system_score_gemma":0.0001623088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002097756,"about_ca_topic_score_gemma":0.00003767482,"domain_scores_codex":[0.9975443,0.0000748758,0.0003953977,0.001062613,0.0003949743,0.0005278771],"domain_scores_gemma":[0.9985544,0.00002683299,0.0003367698,0.0006904576,0.0001927884,0.0001987552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003516764,0.00002913723,0.001079466,0.0002053505,0.0002274577,0.00002251798,0.0001396717,0.0000125611,0.9706723,0.0001833135,0.01367132,0.01340524],"study_design_scores_gemma":[0.0004006306,0.0001153822,0.0008870528,0.0002086436,0.000062541,0.00007448803,0.00002140046,0.00001139019,0.8753079,0.002503837,0.1198018,0.0006048909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961548,0.009391869,0.002302946,0.0002947459,0.004251353,0.0006380702,0.0006333987,0.000084953,0.02085461],"genre_scores_gemma":[0.985293,0.0003916055,0.00587423,0.001250929,0.003175297,0.00002488842,0.001050357,0.00009722153,0.002842476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1061305,"threshold_uncertainty_score":0.9996972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004814477618248917,"score_gpt":0.2521950281545075,"score_spread":0.2473805505362586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}