{"id":"W1520340241","doi":"10.3389/fneur.2015.00123","title":"REM Sleep at its Core – Circuits, Neurotransmitters, and Pathophysiology","year":2015,"lang":"en","type":"review","venue":"Frontiers in Neurology","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroscience; Rapid eye movement sleep; Brainstem; Glutamatergic; Cataplexy; Tegmentum; Neuroscience of sleep; Narcolepsy; Non-rapid eye movement sleep; Psychology; Medicine; Glutamate receptor; Midbrain; Central nervous system; Eye movement; Internal medicine; Neurology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004058692,0.0007056714,0.002444876,0.0008506498,0.0001632734,0.00003735195,0.001129192,0.0009556477,0.00003791919],"category_scores_gemma":[0.0007342856,0.0006284739,0.0002610656,0.0008460304,0.0006553483,0.0001219769,0.0006246445,0.00186085,0.0001349856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001276216,"about_ca_system_score_gemma":0.0001796759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006229874,"about_ca_topic_score_gemma":0.000004942389,"domain_scores_codex":[0.9937474,0.001968867,0.0007666586,0.001906036,0.0004331489,0.001177966],"domain_scores_gemma":[0.9978952,0.0006115127,0.0002918599,0.0008065497,0.00004806645,0.0003468404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001102215,0.00007411061,0.0002124587,0.002565086,0.00002009245,0.002173156,0.00006658298,0.000003732339,0.00009835156,0.0001416202,0.01755216,0.9769824],"study_design_scores_gemma":[0.0006742785,0.0004473246,0.00005217145,0.0002067483,0.0001007941,0.0005843978,0.000002988904,0.0002172442,0.00001757146,0.001097534,0.9960943,0.000504586],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001611962,0.9915022,0.0000465492,0.000248682,0.004046158,0.00147152,0.0001282206,0.00009585929,0.0008488193],"genre_scores_gemma":[0.0003194151,0.9966659,0.0000224255,0.001964478,0.0002201694,0.0003013943,0.0000333723,0.000137855,0.0003350234],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9785422,"threshold_uncertainty_score":0.9996167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1194939153792079,"score_gpt":0.3413456244620042,"score_spread":0.2218517090827962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}