{"id":"W1522355061","doi":"10.1007/s00262-002-0357-4","title":"Exposure to paclitaxel or vinblastine down-regulates CD11a and CD54 expression by P815 mastocytoma cells and renders the tumor cells resistant to killing by nonspecific cytotoxic T lymphocytes induced with anti-CD3 antibody","year":2003,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Mastocytoma; Vinblastine; Cytotoxic T cell; Paclitaxel; Cancer research; CD3; Cytotoxicity; In vitro; Immunology; Biology; Tumor cells; Chemistry; Medicine; Chemotherapy; CD8; Immune system; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007138715,0.0002027721,0.0002542264,0.0001694424,0.0002250313,0.0003243354,0.0002256527,0.0002881531,0.001772727],"category_scores_gemma":[0.00007310222,0.0001876895,0.0002877004,0.0001946833,0.0001611633,0.0001799889,0.0001206732,0.0005494784,0.0004825707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003639323,"about_ca_system_score_gemma":0.00018799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001059802,"about_ca_topic_score_gemma":0.001747194,"domain_scores_codex":[0.9998201,0.00002092662,0.00001302544,0.00002246682,0.00002781021,0.00009579022],"domain_scores_gemma":[0.9999396,0.00001745886,0.00001278889,0.00001267646,0.000004032331,0.00001349971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002400409,0.00003649501,0.000126271,0.00001056265,0.00000447845,0.00008274502,0.00001052436,0.00003305707,0.9987507,0.00008798648,0.00006303896,0.0005540983],"study_design_scores_gemma":[0.00003145574,0.0002569707,0.003893966,0.00000235362,0.00001129349,0.0002143791,0.00002629246,0.0003805932,0.9938402,0.00002795632,0.001312245,0.000002424228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975095,0.0004294417,0.0004798837,0.0000807645,0.00004014267,0.00001203759,0.0001717662,0.00002725401,0.001249177],"genre_scores_gemma":[0.9963641,0.0003419029,0.0004075146,0.00003355406,0.00001000813,0.00001542009,0.0003393912,0.00001076362,0.002477438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001772727,"threshold_uncertainty_score":0.005930364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01731036074328678,"score_gpt":0.2874318637646808,"score_spread":0.270121503021394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}