{"id":"W1523445811","doi":"","title":"AEG33783, a potent JNK pathway inhibitor with neuroprotective properties, selectively induces apoptosis in tumor cell lines","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aegera Therapeutics (Canada)","funders":"","keywords":"Pharmacology; DU145; Vinblastine; Cisplatin; Medicine; Chemosensitizer; Cancer research; Neuroprotection; Clonogenic assay; Paclitaxel; Chemotherapy; Apoptosis; Cytotoxicity; Cancer; Biology; Cancer cell; Internal medicine; LNCaP; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001011328,0.0005933345,0.0003806008,0.0003421228,0.0001931017,0.0002331394,0.0002162482,0.0002629428,0.002306886],"category_scores_gemma":[0.00008376416,0.0001472703,0.0002028703,0.000352687,0.0001554348,0.0002144964,0.0001476355,0.001105884,0.0008865407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003790646,"about_ca_system_score_gemma":0.0003418824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001529195,"about_ca_topic_score_gemma":0.003190228,"domain_scores_codex":[0.9999154,0.00001144241,0.000009478239,0.00001172873,0.00002871271,0.0000232087],"domain_scores_gemma":[0.9999644,0.000005466926,0.000006632959,0.000006389485,0.000007253311,0.00000984795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002388138,0.00009202132,0.00015158,0.00008639666,0.00001601961,0.00008806129,0.0000144906,0.0001830859,0.9905306,0.0001532447,0.0008873842,0.007558294],"study_design_scores_gemma":[0.00007484861,0.0006080613,0.003115746,0.000008108294,0.00002849888,0.0007000465,0.00001573841,0.0008613917,0.9871486,0.00006139166,0.007370773,0.000006841909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9677032,0.01168965,0.005135777,0.0007214192,0.000133948,0.000216591,0.002671064,0.0005076796,0.01122061],"genre_scores_gemma":[0.9754997,0.007871687,0.004717863,0.0001997495,0.00003211755,0.0001319214,0.005305976,0.00004830607,0.006192701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002306886,"threshold_uncertainty_score":0.007717252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06511056408115463,"score_gpt":0.3362190570709432,"score_spread":0.2711084929897886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}