{"id":"W1523989799","doi":"10.1113/jphysiol.2006.120832","title":"C‐type natriuretic peptide activates a non‐selective cation current in acutely isolated rat cardiac fibroblasts via natriuretic peptide C receptor‐mediated signalling","year":2007,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"TRPC3; Natriuretic peptide; Endocrinology; Internal medicine; TRPC5; Brain natriuretic peptide; TRPC; Receptor; Phospholipase C; Transient receptor potential channel; Agonist; NPR2; Atrial natriuretic peptide; Pertussis toxin; Protein kinase C; Chemistry; Biology; Signal transduction; G protein; Cell biology; Heart failure; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002682989,0.0004263702,0.0005886997,0.0001560172,0.0001403873,0.000305883,0.000298688,0.0003634764,0.000966681],"category_scores_gemma":[0.0001564495,0.000171521,0.0005172645,0.0001860075,0.0002197507,0.0003304452,0.0002000302,0.0007866289,0.0003433116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002356058,"about_ca_system_score_gemma":0.0001894371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008545329,"about_ca_topic_score_gemma":0.001190498,"domain_scores_codex":[0.9996889,0.00003826072,0.0000373617,0.00006826171,0.0001029015,0.00006437969],"domain_scores_gemma":[0.9998195,0.00005985969,0.0000311291,0.00002692679,0.00002464537,0.00003800594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000828866,0.00001829741,0.00005711073,0.0000320412,0.000003593123,0.00006489497,0.00001449137,0.00001643218,0.9992954,0.00002175487,0.00001912262,0.0003739264],"study_design_scores_gemma":[0.00007445781,0.0008918401,0.005730132,0.000009111705,0.00003288745,0.0002863336,0.00005291367,0.0008533676,0.9910914,0.00004642936,0.0009221908,0.000009013138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932254,0.002408904,0.002266997,0.000101444,0.00007963811,0.00003321644,0.0004527209,0.00005622629,0.001375449],"genre_scores_gemma":[0.9916651,0.001606814,0.003982644,0.0001517193,0.00003923455,0.00007873345,0.0006554879,0.00001904619,0.001801285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000966681,"threshold_uncertainty_score":0.00323385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01641899063518048,"score_gpt":0.2725609457381699,"score_spread":0.2561419551029894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}