{"id":"W1524575989","doi":"10.1046/j.1529-8817.2003.00124.x","title":"Linkage Disequilibrium and Haplotype Architecture for two ABC Transporter Genes (<i>ABCC1</i> and <i>ABCG2</i>) in Chinese Population: Implications for Pharmacogenomic Association Studies","year":2004,"lang":"en","type":"article","venue":"Annals of Human Genetics","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Fudan University","keywords":"Linkage disequilibrium; Genetics; Haplotype; Biology; Single-nucleotide polymorphism; Genetic association; Locus (genetics); Gene; Association mapping; ABCC1; Tag SNP; Allele; ATP-binding cassette transporter; Genotype; Transporter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009127607,0.0001701374,0.0003700247,0.001173432,0.0005470982,0.0003391913,0.0002093017,0.000213037,0.001376086],"category_scores_gemma":[0.001693467,0.0001505901,0.0002794064,0.001342292,0.0007407566,0.0002240939,0.0002698517,0.00022933,0.0001173286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004279175,"about_ca_system_score_gemma":0.0004223953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01053204,"about_ca_topic_score_gemma":0.01130138,"domain_scores_codex":[0.9994335,0.0001796382,0.00004338317,0.0001897526,0.00007266962,0.00008103172],"domain_scores_gemma":[0.9992366,0.0002945539,0.0001762855,0.0001051452,0.00007412944,0.000113371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003784243,0.00004428317,0.9638431,0.00002772589,0.0002147764,0.00062928,0.001153371,0.0008887601,0.01825477,0.0008135758,0.000141797,0.01361015],"study_design_scores_gemma":[0.000027293,0.00007602973,0.996999,0.000003587507,0.00007656198,0.0003755477,0.0001278458,0.001082184,0.0004934691,0.0005030342,0.0002249385,0.00001037107],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992618,0.00008687367,0.0003538537,0.00003198941,0.000001405314,0.000005163641,0.00006479706,0.000002094153,0.0001919879],"genre_scores_gemma":[0.9994559,0.00006137826,0.0002130713,0.00001121623,0.000005124159,0.000006973556,0.0001275301,0.000001867476,0.0001168649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01053204,"threshold_uncertainty_score":0.0209415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05405978089511921,"score_gpt":0.384106072438172,"score_spread":0.3300462915430528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}