{"id":"W1524698046","doi":"10.1593/neo.07965","title":"Differential Expression of Secretory Phospholipases A2 in Normal and Malignant Prostate Cell Lines: Regulation by Cytokines, Cell Signaling Pathways, and Epigenetic Mechanisms","year":2008,"lang":"en","type":"article","venue":"Neoplasia","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Institute for Biodiagnostics; National Research Council Canada","funders":"","keywords":"LNCaP; Biology; Signal transduction; Kinase; Molecular biology; Protein kinase A; DNA methylation; Cancer research; Gene expression; Cell biology; Cancer cell; Biochemistry; Gene; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001355574,0.0002462737,0.0001810044,0.0004191813,0.0001539957,0.0004461482,0.0001027075,0.0001666718,0.0007513146],"category_scores_gemma":[0.0001310089,0.0001345048,0.0002123177,0.0003708758,0.0002141087,0.0002359157,0.000198185,0.0003347298,0.0002405834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046778,"about_ca_system_score_gemma":0.0001545652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004138632,"about_ca_topic_score_gemma":0.0004695831,"domain_scores_codex":[0.9998388,0.00002522057,0.00001678673,0.00004120592,0.00004479566,0.00003303945],"domain_scores_gemma":[0.9998668,0.00002312826,0.0000309926,0.00002461985,0.00002423594,0.0000302353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001466719,0.00001559218,0.001876129,0.00003357203,0.0000075016,0.00006615964,0.00003855232,0.00002019376,0.9966314,0.00004472471,0.00002869449,0.001090769],"study_design_scores_gemma":[0.00002195314,0.000528658,0.0669309,0.000006138836,0.00005095877,0.001369733,0.0002322173,0.0006037315,0.9265299,0.00009805348,0.003615571,0.00001230649],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925966,0.00342477,0.002245516,0.00005278502,0.00001956437,0.00002550439,0.0006147331,0.00006110429,0.0009595033],"genre_scores_gemma":[0.9949341,0.001412987,0.001103729,0.0000325922,0.00001687602,0.00004952032,0.0011561,0.00001015823,0.001283965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007513146,"threshold_uncertainty_score":0.002513409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006735859617432031,"score_gpt":0.1886291864639446,"score_spread":0.1818933268465126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}