{"id":"W1524698046","doi":"10.1593/neo.07965","title":"Differential Expression of Secretory Phospholipases A2 in Normal and Malignant Prostate Cell Lines: Regulation by Cytokines, Cell Signaling Pathways, and Epigenetic Mechanisms","year":2008,"lang":"en","type":"article","venue":"Neoplasia","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Institute for Biodiagnostics; National Research Council Canada","funders":"","keywords":"LNCaP; Biology; Signal transduction; Kinase; Molecular biology; Protein kinase A; DNA methylation; Cancer research; Gene expression; Cell biology; Cancer cell; Biochemistry; Gene; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008718178,0.0001907986,0.0001960031,0.00006591255,0.00009174147,0.00001272156,0.00006144726,0.0001707854,0.00002688332],"category_scores_gemma":[0.00001273033,0.000181022,0.00004008119,0.00006925628,0.00007745955,0.00001049923,0.00008085169,0.00007277726,6.126128e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008730673,"about_ca_system_score_gemma":0.00005435166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002974895,"about_ca_topic_score_gemma":0.000006262464,"domain_scores_codex":[0.9988828,0.00007074166,0.0003219208,0.000358946,0.0001580451,0.0002074921],"domain_scores_gemma":[0.9995146,0.00001451204,0.0001665602,0.0001626531,0.00005080023,0.00009090315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001627181,0.00007015799,0.001946429,0.0001069953,0.000003176996,0.000008112828,0.0002062858,0.0002224545,0.9968201,0.00001012102,0.00005675635,0.0003866998],"study_design_scores_gemma":[0.001201748,0.0002032572,0.002966193,0.000079462,0.00001123068,0.00002005069,0.00007105267,0.0007281248,0.9942286,0.00008770114,0.0002036794,0.0001989273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914758,0.002599344,0.005480994,0.000008391841,0.00004390284,0.0002889968,0.00005032186,0.00001056603,0.00004163447],"genre_scores_gemma":[0.9974553,0.000605133,0.001461565,0.00002414517,0.00004919839,0.00002336045,0.000226,0.00002395346,0.000131345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005979451,"threshold_uncertainty_score":0.7381864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006735859617432031,"score_gpt":0.1886291864639446,"score_spread":0.1818933268465126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}