{"id":"W1526800677","doi":"10.1111/j.1524-475x.2010.00635.x","title":"Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute","year":2010,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; CD31; Infiltration (HVAC); Immune system; Cancer research; Immunology; Keratinocyte; Wound healing; Cell; CD3; Medicine; Cell biology; Chemistry; Angiogenesis; Biology; CD8; Cell culture; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001372334,0.0001255553,0.0001538464,0.0001328118,0.00009406362,0.00001757323,0.00007881186,0.0001567296,0.00003256841],"category_scores_gemma":[0.0001510215,0.00009906917,0.00005508035,0.0002146081,0.0001814988,0.0002541542,0.0000234215,0.0001386066,0.000001550595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006540896,"about_ca_system_score_gemma":0.00004022596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004402321,"about_ca_topic_score_gemma":0.00009982064,"domain_scores_codex":[0.9990082,0.00008288501,0.0002719088,0.000303415,0.0002049652,0.0001286593],"domain_scores_gemma":[0.9994102,0.00007575331,0.0001202809,0.0002584803,0.00006108131,0.00007424822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008133433,0.0002034233,0.00002138735,0.00006478541,0.000001801691,0.000002842412,0.0002355558,0.0007565802,0.9975569,0.0002179315,0.00011903,0.0007384648],"study_design_scores_gemma":[0.0006742702,0.0001547175,0.001051136,0.00001819189,0.000003993341,0.00001309493,0.00008148853,0.009271848,0.988107,0.00005192623,0.0004567986,0.0001155398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964287,0.0001328178,0.002633012,0.00002071799,0.0003047131,0.0002112185,0.00001645436,0.00008776503,0.0001645545],"genre_scores_gemma":[0.9986665,0.00007105011,0.0009020462,0.00002695696,0.00009053112,0.00001074297,0.00003645466,0.00001364959,0.0001820239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009449868,"threshold_uncertainty_score":0.4039924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009948246631120051,"score_gpt":0.2257011817349022,"score_spread":0.2157529351037822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}