{"id":"W1526849486","doi":"10.1111/j.1365-2958.2010.07244.x","title":"<i>Vibrio cholerae</i> El Tor TcpA crystal structure and mechanism for pilus‐mediated microcolony formation","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC; U.S. Department of Energy","keywords":"Pilus; Pilin; Vibrio cholerae; Biology; Fimbriae Proteins; Protein subunit; El Tor; Microbiology; Protein filament; Virulence; Biophysics; Bacteria; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001360426,0.0002808143,0.0002684251,0.00007551497,0.0001717933,0.00004833579,0.0002431194,0.000438298,0.00002257589],"category_scores_gemma":[0.0002291348,0.0002642735,0.000104439,0.00006812534,0.0002101646,0.000010503,0.0003028229,0.0002318223,0.000006839992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001754373,"about_ca_system_score_gemma":0.00005833388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001394495,"about_ca_topic_score_gemma":0.0001260743,"domain_scores_codex":[0.9985612,0.00007588771,0.000264117,0.0005225434,0.00005118601,0.0005250711],"domain_scores_gemma":[0.9991748,0.0000243075,0.000114379,0.0003431859,0.0002330601,0.0001102567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001424386,0.0000250349,0.00007446622,0.00004481159,0.0000891256,0.00000406753,0.00006107249,7.574066e-7,0.9973193,0.0004593239,0.001623085,0.0001565371],"study_design_scores_gemma":[0.001383327,0.0004025443,0.0001903738,0.00000573096,0.00002310164,0.0001963155,0.00002111848,0.00002311045,0.9288883,0.0004132725,0.06817108,0.0002816773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992282,0.0002738159,0.004817921,0.0006623885,0.0003187163,0.0008615669,0.0006988826,0.00002608042,0.00005862668],"genre_scores_gemma":[0.9925083,0.00006179282,0.003953224,0.001403299,0.0001935102,0.0001152584,0.001632122,0.00004482176,0.00008766679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06843094,"threshold_uncertainty_score":0.9999809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004055705534128278,"score_gpt":0.2333493472379005,"score_spread":0.2292936417037722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}