{"id":"W1526872267","doi":"10.1111/j.1755-148x.2010.00715.x","title":"Alpha 1 antichymotrypsin is aberrantly expressed during melanoma progression and predicts poor survival for patients with metastatic melanoma","year":2010,"lang":"en","type":"letter","venue":"Pigment Cell & Melanoma Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Vancouver General Hospital; Vancouver Coastal Health; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"ACT-X; Canadian Institutes of Health Research","keywords":"Melanoma; Medicine; Metastasis; Cancer research; Immunohistochemistry; Oncology; Pathology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000294623,0.0002768507,0.0003242605,0.0005703048,0.000304803,0.0005054732,0.0001985722,0.0004598728,0.001540709],"category_scores_gemma":[0.001052588,0.0001592292,0.0003455649,0.0005426518,0.0001782348,0.0003778295,0.0002491382,0.0008256744,0.0003890089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001276816,"about_ca_system_score_gemma":0.0001504899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007870785,"about_ca_topic_score_gemma":0.00141851,"domain_scores_codex":[0.9998859,0.00002274104,0.00001695414,0.00002945139,0.00002399973,0.00002103289],"domain_scores_gemma":[0.999203,0.0001162885,0.0003609455,0.00003581046,0.00009491132,0.000189054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002101864,0.0000189713,0.9951455,0.00002199473,0.00003309913,0.000327316,0.00002562808,0.00004589906,0.001182635,0.00001436709,0.0003256045,0.002648706],"study_design_scores_gemma":[0.000007658684,0.0001190866,0.9960923,0.00001286287,0.00005761014,0.001977652,0.00009802993,0.0005194797,0.0002877989,0.0000718673,0.0007491991,0.000006519184],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957105,0.002735824,0.0001643262,0.000225689,0.00003972567,0.000008116599,0.0003485811,0.00001091349,0.0007563069],"genre_scores_gemma":[0.998607,0.0005504127,0.0001311082,0.00004423923,0.00005439167,0.000005041768,0.0002798,0.000002116558,0.0003259351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540709,"threshold_uncertainty_score":0.005154252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02226164952748986,"score_gpt":0.2897345751395984,"score_spread":0.2674729256121085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}