{"id":"W1527097930","doi":"10.1111/ajt.12287","title":"Comprehensive Assessment and Standardization of Solid Phase Multiplex-Bead Arrays for the Detection of Antibodies to HLA","year":2013,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":243,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Diagnostic Services Manitoba","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service","keywords":"Multiplex; Medicine; Reproducibility; Normalization (sociology); Standardization; Transplantation; Antibody; Standard operating procedure; Immunology; Internal medicine; Chromatography; Bioinformatics; Computer science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01638539,0.0009427251,0.000823481,0.00219766,0.0008309124,0.002069659,0.001354077,0.001340465,0.0007790279],"category_scores_gemma":[0.02053325,0.0007339564,0.0006706921,0.001523608,0.00120306,0.0008071489,0.001591483,0.001514553,0.0004469118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00118744,"about_ca_system_score_gemma":0.002152236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002245212,"about_ca_topic_score_gemma":0.00420821,"domain_scores_codex":[0.9773062,0.008263249,0.002186452,0.003015804,0.008569995,0.0006582424],"domain_scores_gemma":[0.9871689,0.004294937,0.00164464,0.002683323,0.00396595,0.0002422016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007707521,0.0007564599,0.07826084,0.0004604687,0.0005157524,0.00007154066,0.0009580528,0.005687033,0.7772743,0.002452399,0.002208258,0.1305842],"study_design_scores_gemma":[0.000109042,0.001665948,0.1633754,0.0001491353,0.000518552,0.000994309,0.0003816088,0.02703108,0.7873794,0.002064914,0.01622558,0.0001049518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5913519,0.005388316,0.3878014,0.001038056,0.0003219277,0.001967055,0.003387832,0.00175223,0.006991228],"genre_scores_gemma":[0.7617384,0.001119653,0.2276302,0.0009695153,0.0001072775,0.001352956,0.004775787,0.0001659685,0.002140184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01638539,"threshold_uncertainty_score":0.08665526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02327699557379588,"score_gpt":0.3782963256599414,"score_spread":0.3550193300861456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}