{"id":"W1527262512","doi":"10.1080/15384101.2014.1000182","title":"Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis","year":2015,"lang":"en","type":"article","venue":"Cell Cycle","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"Deutsche Forschungsgemeinschaft","keywords":"Biology; Origin recognition complex; Mitosis; Cell biology; Centrosome; Chromatin; Licensing factor; DNA replication factor CDT1; Cell cycle; Control of chromosome duplication; Genome instability; Pre-replication complex; DNA replication; Genetics; Eukaryotic DNA replication; Cell; DNA; DNA damage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012051,0.0001271024,0.0001266642,0.0003022913,0.0001714128,0.000489136,0.0001600488,0.0001295762,0.0008029497],"category_scores_gemma":[0.0001906375,0.000130925,0.00008966933,0.0001342311,0.000216681,0.0002513674,0.0002510707,0.0001443161,0.0003769786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004696858,"about_ca_system_score_gemma":0.0002062458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018633,"about_ca_topic_score_gemma":0.001763113,"domain_scores_codex":[0.9999201,0.00001065638,0.000006439879,0.00002422568,0.00002422016,0.00001437971],"domain_scores_gemma":[0.9999093,0.00001905659,0.00002173239,0.00001282223,0.00001566908,0.00002149157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001337311,0.000007484939,0.0007186926,0.00002001439,0.000001708919,0.00005031958,0.00002253414,0.00009902953,0.9959821,0.0003809719,0.00002917116,0.002554388],"study_design_scores_gemma":[0.00001182772,0.00006562311,0.0264791,0.00001040293,0.000007004486,0.0003146676,0.00006324566,0.002327268,0.9666705,0.0003830454,0.003659874,0.00000736795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815685,0.01027513,0.004024958,0.0001068801,0.00002606882,0.00001766017,0.0003075857,0.00009909637,0.003574103],"genre_scores_gemma":[0.9965351,0.001190318,0.0009120327,0.00001452356,0.000007461904,0.000005341211,0.0001148976,0.00001409196,0.001206316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001018633,"threshold_uncertainty_score":0.003407836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0174173078258599,"score_gpt":0.2479332392626259,"score_spread":0.230515931436766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}