{"id":"W1527378674","doi":"10.1002/9780470514924.ch5","title":"Proteoglycans and Amyloid Fibrillogenesis","year":2007,"lang":"en","type":"article","venue":"Novartis Foundation symposium","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Kingston General Hospital","funders":"","keywords":"Fibrillogenesis; Chemistry; Amyloid (mycology); In vivo; Perlecan; Heparan sulfate; Proteoglycan; In vitro; Amyloidosis; Biochemistry; Amyloid disease; Amyloid fibril; Biophysics; Cell biology; Glycosaminoglycan; Amyloid β; Biology; Pathology; Extracellular matrix; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001696705,0.0003194995,0.0001156699,0.0005017624,0.0002818655,0.0003699358,0.0001388992,0.0004272892,0.001101157],"category_scores_gemma":[0.00009367083,0.00008255477,0.0001157242,0.0004000861,0.0004982363,0.0003407974,0.0003505201,0.0005140604,0.000299644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000465641,"about_ca_system_score_gemma":0.0002706169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001098453,"about_ca_topic_score_gemma":0.001487377,"domain_scores_codex":[0.9999348,0.00001874455,0.00000640307,0.00000838879,0.00001644599,0.00001521623],"domain_scores_gemma":[0.9999589,0.00001190779,0.000009642484,0.00000169116,0.000005045205,0.00001291032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000513967,0.0002029888,0.003285351,0.003221725,0.00007674562,0.005408632,0.0009528485,0.002519272,0.4572162,0.1721914,0.01935445,0.3350563],"study_design_scores_gemma":[0.00002786005,0.0005890281,0.02752748,0.0006932889,0.00004680307,0.008257019,0.0004037951,0.0007301765,0.09771796,0.06432535,0.7996185,0.00006271298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.06661524,0.8902088,0.006192538,0.00474178,0.001033922,0.00004215246,0.0001548884,0.0000631659,0.03094753],"genre_scores_gemma":[0.2968909,0.6513405,0.005521319,0.002230711,0.001300476,0.00004164529,0.0003052944,0.00001754822,0.04235167],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001101157,"threshold_uncertainty_score":0.003683746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122901876741,"score_gpt":0.2824755956513774,"score_spread":0.2701854079772774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}