{"id":"W1527378674","doi":"10.1002/9780470514924.ch5","title":"Proteoglycans and Amyloid Fibrillogenesis","year":2007,"lang":"en","type":"article","venue":"Novartis Foundation symposium","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Kingston General Hospital","funders":"","keywords":"Fibrillogenesis; Chemistry; Amyloid (mycology); In vivo; Perlecan; Heparan sulfate; Proteoglycan; In vitro; Amyloidosis; Biochemistry; Amyloid disease; Amyloid fibril; Biophysics; Cell biology; Glycosaminoglycan; Amyloid β; Biology; Pathology; Extracellular matrix; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005915827,0.000177303,0.0001369193,0.0001198134,0.0001983677,0.00008574793,0.00015426,0.0001597532,0.00009268418],"category_scores_gemma":[0.00006693209,0.0001755191,0.00005600536,0.0002152815,0.0001610406,0.00001422557,0.000132671,0.00009071641,0.00005569664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003152231,"about_ca_system_score_gemma":0.00009657995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001036083,"about_ca_topic_score_gemma":0.0002434835,"domain_scores_codex":[0.9985118,0.00004420019,0.0002833678,0.0004649417,0.0002613029,0.0004343838],"domain_scores_gemma":[0.9991993,0.00001715916,0.00007506977,0.0003610444,0.0001707286,0.0001766448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001889685,0.00003400905,0.008178785,0.00002006809,0.00003140384,0.000005934818,0.00005656178,0.000005835509,0.9669018,0.0003736152,0.0004073693,0.02379567],"study_design_scores_gemma":[0.0007394548,0.0004272107,0.01736314,0.00001076072,0.00001283573,0.00008928645,0.00005472388,0.00005656618,0.7443976,0.0001138878,0.2364321,0.0003023757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961265,0.0001852836,0.03000309,0.0007964999,0.0001723943,0.0005601504,0.00001301617,0.00003426216,0.006970354],"genre_scores_gemma":[0.9936773,0.0001635886,0.002131923,0.0002828536,0.0003767149,0.00005082284,0.0001383812,0.00003252754,0.003145871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2360247,"threshold_uncertainty_score":0.715746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122901876741,"score_gpt":0.2824755956513774,"score_spread":0.2701854079772774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}