{"id":"W1527471222","doi":"10.1007/978-0-387-73657-0_37","title":"Subtilisin Kexin Isozyme-1 (SKI-1): Production, purification, inhibitor design and biochemical applications","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Subtilisin; Kexin; Isozyme; Chemistry; Biochemistry; Pharmacology; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004794403,0.0005840186,0.0004141542,0.0004150229,0.0001631502,0.0004895758,0.0002991231,0.0002903393,0.0002999139],"category_scores_gemma":[0.0004079669,0.0003084569,0.000226594,0.0004186829,0.0002263864,0.0004163208,0.0002007469,0.0008398452,0.0004121778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005699772,"about_ca_system_score_gemma":0.0004994234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000640621,"about_ca_topic_score_gemma":0.000718243,"domain_scores_codex":[0.9997993,0.00002545456,0.00003400672,0.00003923553,0.0000800433,0.00002193889],"domain_scores_gemma":[0.9998062,0.00004042973,0.00005381531,0.00001475451,0.00004505267,0.00003974277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001435245,0.00003951684,0.0003663071,0.0001263113,0.00000627792,0.00002684718,0.00001586613,0.0002493388,0.9891237,0.00008763007,0.00005972142,0.009754943],"study_design_scores_gemma":[0.00000899521,0.00007628754,0.0009160357,0.000006348543,0.00001511187,0.0002247386,0.000005746814,0.0006034269,0.9957026,0.0000342531,0.002402595,0.000003954341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9106339,0.02478695,0.06025693,0.0009127617,0.00007774866,0.0001642243,0.0008457492,0.0003827878,0.001939035],"genre_scores_gemma":[0.9208644,0.0179941,0.05401832,0.0001096954,0.00004842253,0.00008396607,0.00307758,0.00006726222,0.003736168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000640621,"threshold_uncertainty_score":0.004135549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01258834157106548,"score_gpt":0.3017986523245455,"score_spread":0.28921031075348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}