{"id":"W1527721714","doi":"10.1023/a:1015490531653","title":"Kinetic Analysis of Multi Enzyme Systems: A Case Study of the Closed System of Creatine Kinase, Hexokinase and Glucose 6-Phosphate Dehydrogenase","year":2002,"lang":"en","type":"article","venue":"Journal of Mathematical Chemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Hexokinase; Yeast; Computation; Enzyme; Dehydrogenase; Chemistry; Mathematics; Biochemistry; Computer science; Algorithm; Glycolysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001702992,0.0007096667,0.00108,0.0006585741,0.0007782443,0.001874325,0.001186086,0.001734437,0.001755786],"category_scores_gemma":[0.004596913,0.0004521577,0.001165371,0.0005722086,0.001480971,0.00148121,0.00105524,0.001172473,0.0001412267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001141368,"about_ca_system_score_gemma":0.0005966156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004143941,"about_ca_topic_score_gemma":0.00172262,"domain_scores_codex":[0.999323,0.0002955084,0.00004386062,0.00009178359,0.000166354,0.00007959877],"domain_scores_gemma":[0.9956493,0.003466169,0.0002664216,0.000162983,0.0003212671,0.000133852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002898325,0.0003352102,0.003209487,0.0002423467,0.0001314713,0.001858779,0.0006865657,0.853222,0.0118962,0.1087789,0.0004778533,0.01887139],"study_design_scores_gemma":[0.00001795067,0.00006889476,0.0005778057,0.000005656872,0.0000238155,0.0001599812,0.0001029233,0.9813302,0.0009742047,0.01630182,0.0004198217,0.00001690549],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.479342,0.002361548,0.5024765,0.001061693,0.0000507225,0.0001145341,0.0000903909,0.0001856596,0.014317],"genre_scores_gemma":[0.9794267,0.0004058972,0.01679357,0.00002547804,0.00003012517,0.00003655057,0.00002898633,0.00002007778,0.003232479],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004143941,"threshold_uncertainty_score":0.009006381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782690690608048,"score_gpt":0.237331939389103,"score_spread":0.2195050324830225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}