{"id":"W1527901818","doi":"10.1002/eji.201141801","title":"NHERF1 regulates gp120‐induced internalization and signaling by CCR5, and HIV‐1 production","year":2011,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Cell biology; Scaffold protein; Biology; RHOA; Signal transduction; Focal adhesion; Chemokine; MAPK/ERK pathway; Chemokine receptor; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183213,0.0002126411,0.0001891165,0.0001338243,0.0002066675,0.0002675119,0.0001566939,0.0002941963,0.0009843305],"category_scores_gemma":[0.00008672298,0.0001216111,0.0002733258,0.00008854956,0.0001844211,0.0002097805,0.000149229,0.00039047,0.0002543484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005177129,"about_ca_system_score_gemma":0.0001395883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001330593,"about_ca_topic_score_gemma":0.00161076,"domain_scores_codex":[0.9998806,0.00001339248,0.000008268444,0.0000235825,0.00002506033,0.00004917907],"domain_scores_gemma":[0.9999498,0.000005471593,0.00001584948,0.000004602317,0.000006452168,0.0000177747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001466014,0.00002200331,0.000203753,0.00002540376,0.000002606988,0.00004946318,0.00001195836,0.00002702951,0.998801,0.00007580937,0.00005217005,0.0005822119],"study_design_scores_gemma":[0.00005329127,0.0003212768,0.04166695,0.00001356269,0.00002770949,0.0003659256,0.00007774307,0.001448479,0.9523529,0.00007870615,0.003584758,0.000008764214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99497,0.002968868,0.0006193361,0.00007990989,0.0000192641,0.00001783838,0.0003039032,0.00002614781,0.0009948309],"genre_scores_gemma":[0.9956272,0.0009131744,0.0006468683,0.00004480569,0.00001153117,0.00002470896,0.0006073616,0.000008445921,0.002115928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001330593,"threshold_uncertainty_score":0.003756285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02345187679297444,"score_gpt":0.2226996706850143,"score_spread":0.1992477938920398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}