{"id":"W1528144459","doi":"10.1212/wnl.82.10_supplement.p3.173","title":"4-Year Follow-up of Delayed-Release Dimethyl Fumarate Treatment in Relapsing-Remitting Multiple Sclerosis (RRMS): Integrated Clinical Efficacy Data From DEFINE, CONFIRM, and the ENDORSE Extension Study (P3.173)","year":2014,"lang":"en","type":"article","venue":"Neurology","topic":"Fungal Plant Pathogen Control","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Dimethyl fumarate; Relapsing remitting; Multiple sclerosis; Medicine; Clinical efficacy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0062945,0.0008182178,0.002216084,0.0006163377,0.0007012659,0.000782527,0.0006393592,0.001076445,0.00188091],"category_scores_gemma":[0.004531845,0.0004872083,0.001485406,0.0004668234,0.000499555,0.001258876,0.0007301484,0.00182894,0.0005160022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005149966,"about_ca_system_score_gemma":0.0005038303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009798603,"about_ca_topic_score_gemma":0.001674287,"domain_scores_codex":[0.9985101,0.0006775849,0.0001461157,0.0001762887,0.0002815407,0.000208312],"domain_scores_gemma":[0.9946107,0.0009706484,0.001942529,0.0007639442,0.0008506076,0.000861656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5418585,0.01372742,0.3574386,0.0005463588,0.004703172,0.00036107,0.000560832,0.001139815,0.009498418,0.00009246833,0.003425784,0.06664746],"study_design_scores_gemma":[0.04449508,0.1279562,0.8171841,0.00006555764,0.003207416,0.0003949549,0.0001979171,0.0007447462,0.002814327,0.0001019318,0.00276242,0.00007538733],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955603,0.001278732,0.00018667,0.00008066044,0.00002808098,0.000317683,0.001672379,0.00002918604,0.0008463467],"genre_scores_gemma":[0.9937167,0.000309143,0.0003790894,0.0001746258,0.00005460936,0.0002735113,0.004216329,0.000009055077,0.0008669854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0062945,"threshold_uncertainty_score":0.0332889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07878279473828251,"score_gpt":0.2669008618078413,"score_spread":0.1881180670695588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}