{"id":"W1528825864","doi":"10.1002/9780470015902.a0024873","title":"Mitochondrial <scp>DNA</scp> Copy Number Alterations in Human Cancers","year":2012,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Tianjin Science and Technology Committee; Beijing Municipal Science and Technology Commission","keywords":"Mitochondrial DNA; Biology; Mitochondrion; Cancer; Oxidative phosphorylation; Cancer cell; Carcinogenesis; Cancer research; Genetics; Somatic cell; Mitochondrial disease; Cell biology; Molecular biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002149205,0.0001535533,0.0001487321,0.002009078,0.0001384562,0.0004803904,0.0001879364,0.0002269719,0.008361257],"category_scores_gemma":[0.0006933457,0.00006233536,0.0001135633,0.002029612,0.0001790114,0.000212706,0.0002919231,0.0001634698,0.001802534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001944828,"about_ca_system_score_gemma":0.0001465423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009043261,"about_ca_topic_score_gemma":0.0008626946,"domain_scores_codex":[0.9998641,0.00001575056,0.00001713256,0.00003829105,0.00005370271,0.00001090789],"domain_scores_gemma":[0.9997134,0.00006637118,0.00009839803,0.00002512472,0.00007329007,0.0000233329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001345218,0.0001091145,0.2791227,0.002892827,0.00020126,0.003743561,0.0003450212,0.001119387,0.1014438,0.002307263,0.02086429,0.5865056],"study_design_scores_gemma":[0.00002904006,0.0001838822,0.7244064,0.000522812,0.0002677725,0.02555766,0.000370559,0.001791664,0.05762033,0.003704244,0.1855019,0.00004376508],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.7301244,0.1631071,0.009194701,0.001633884,0.0004036861,0.000149341,0.03422135,0.0008542891,0.06031133],"genre_scores_gemma":[0.9290634,0.03448429,0.005545349,0.0001805109,0.0001284345,0.00007294679,0.009041427,0.00006125847,0.02142241],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.008361257,"threshold_uncertainty_score":0.02797115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487679253608946,"score_gpt":0.2832630838432098,"score_spread":0.2683862913071203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}