{"id":"W1528874194","doi":"10.1186/1471-2334-4-34","title":"A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection","year":2004,"lang":"en","type":"article","venue":"BMC Infectious Diseases","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Brain Injury Research Center; Henan Institute of Science and Technology; Singapore Millennium Foundation; Centers for Disease Control and Prevention; Singapore General Hospital; Canterbury Medical Research Foundation; Consortium canadien en neurodégénérescence associée au vieillissement; State Key Laboratory of Automotive Simulation and Control; Technology Agency of the Czech Republic; Genome Institute of Singapore; Agency for Science, Technology and Research; Hakai Institute","keywords":"Immunology; Peripheral blood mononuclear cell; Chemokine; Immune system; Biology; Pathogenesis; Viral replication; Coronavirus; Virology; Medical microbiology; Antibody; Inflammation; Medicine; In vitro; Virus; Infectious disease (medical specialty); Disease; Pathology; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009362182,0.0006216535,0.0007525305,0.0004284926,0.0003639915,0.0007753737,0.0005146374,0.0005747936,0.004305267],"category_scores_gemma":[0.0002876699,0.0002139104,0.0005190664,0.0005080456,0.0002920019,0.0002622238,0.0003542039,0.001182319,0.002141548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005556571,"about_ca_system_score_gemma":0.0004953114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009058741,"about_ca_topic_score_gemma":0.001665038,"domain_scores_codex":[0.9988298,0.0004299214,0.0001069097,0.0002484838,0.0002601209,0.0001247117],"domain_scores_gemma":[0.9996506,0.0001085065,0.00005079784,0.00009347217,0.00005980649,0.00003677442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008099596,0.0004064363,0.001073261,0.0005444817,0.00005615883,0.0002824526,0.00009005294,0.0005449633,0.9900462,0.0006237259,0.001682131,0.003840112],"study_design_scores_gemma":[0.000197924,0.004823355,0.007117262,0.00008043058,0.0002351547,0.001960547,0.0001830809,0.004061747,0.9396817,0.0004569767,0.04116064,0.0000411609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7564112,0.04474533,0.1427881,0.002230998,0.00273863,0.001676076,0.02473203,0.001435529,0.02324207],"genre_scores_gemma":[0.8951027,0.01482393,0.05540719,0.0009312899,0.0004100985,0.0021065,0.01981312,0.0001132126,0.01129202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004305267,"threshold_uncertainty_score":0.01440257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09675041116747966,"score_gpt":0.4237103267178322,"score_spread":0.3269599155503525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}