{"id":"W1528980109","doi":"10.1111/j.1471-4159.2009.05978.x","title":"Hypoxic stress‐induced changes in adrenergic function: role 
 of HIF1α","year":2009,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; McLean Hospital","keywords":"Phenylethanolamine; Phenylethanolamine N-methyltransferase; Luciferase; Epinephrine; Messenger RNA; Hypoxia (environmental); Gene expression; Adrenal medulla; Chemistry; Hypoxia-inducible factors; Biology; Stimulation; Molecular biology; Cell biology; Endocrinology; Internal medicine; Catecholamine; Transfection; Gene; Biochemistry; Enzyme; Tyrosine hydroxylase; Medicine; Oxygen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183906,0.0002543351,0.0001624727,0.0001163987,0.0001426741,0.0002227916,0.000134063,0.0002208265,0.001238781],"category_scores_gemma":[0.00007412761,0.00008983786,0.0001729313,0.00007649545,0.0001656517,0.0001613525,0.0001173416,0.0003048329,0.0002087865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003274122,"about_ca_system_score_gemma":0.0001168578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005005763,"about_ca_topic_score_gemma":0.0007225144,"domain_scores_codex":[0.9999468,0.000009422011,0.000003221246,0.0000121839,0.00001081143,0.0000174426],"domain_scores_gemma":[0.9999435,0.000006146021,0.00001394589,0.000005342838,0.000008993981,0.0000220846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000185866,0.00002472384,0.000805624,0.00005444277,0.000007638767,0.00007925676,0.00001978064,0.00004504988,0.9951518,0.0001071977,0.0000573882,0.003461367],"study_design_scores_gemma":[0.00002960973,0.0009064959,0.156838,0.00004506221,0.00005198638,0.001221788,0.0001658245,0.0008978787,0.8339366,0.0003685776,0.005526569,0.00001161795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9687757,0.02007467,0.004890291,0.0005639101,0.0001053111,0.00006135555,0.0005556357,0.00009297602,0.004880103],"genre_scores_gemma":[0.9878033,0.006244221,0.001488137,0.0002068212,0.00007997017,0.00004546865,0.0004238215,0.00001296791,0.003695317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001238781,"threshold_uncertainty_score":0.004144192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007891051916990159,"score_gpt":0.2281398430397812,"score_spread":0.220248791122791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}