{"id":"W1530075337","doi":"10.3390/biom5031441","title":"Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins","year":2015,"lang":"en","type":"article","venue":"Biomolecules","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; York University; Zegar Family Foundation; National Institute of General Medical Sciences; U.S. Department of Defense","keywords":"Interactome; Biology; RNA splicing; RNA; Computational biology; Ribonucleoprotein; Protein–protein interaction; Stress granule; RNA-binding protein; Helicase; RNA Helicase A; Translation (biology); Genetics; Cell biology; Messenger RNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001727772,0.0003493751,0.0003117878,0.0007091305,0.000269331,0.0002271766,0.0001719415,0.0002565538,0.001068273],"category_scores_gemma":[0.0001851156,0.0001289991,0.0003171651,0.0004414692,0.0001119601,0.000153782,0.000336978,0.0002139002,0.0003032439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001830748,"about_ca_system_score_gemma":0.0001140539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004402079,"about_ca_topic_score_gemma":0.0007346674,"domain_scores_codex":[0.9998392,0.00001494375,0.00001226962,0.00005356434,0.00005700775,0.0000230672],"domain_scores_gemma":[0.999898,0.00002107191,0.00002511669,0.00001004096,0.00001612426,0.00002969644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008223322,0.00001088634,0.002815637,0.0000360511,0.00002038327,0.00008219591,0.00001296471,0.00005330817,0.9956678,0.00001667263,0.00004276016,0.001159021],"study_design_scores_gemma":[0.00001940639,0.0002446512,0.2633041,0.000008283361,0.0001009555,0.002339196,0.00007065968,0.00509631,0.7256438,0.00009945813,0.003056205,0.0000169912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932492,0.000685671,0.003712536,0.00003780324,0.00000411375,0.0000255213,0.001919899,0.00009217248,0.0002731712],"genre_scores_gemma":[0.9819807,0.0004977757,0.01056918,0.00006203246,0.000006153718,0.00005338569,0.005703172,0.00002860232,0.001098858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001068273,"threshold_uncertainty_score":0.003573716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03197975840294504,"score_gpt":0.3060826661731282,"score_spread":0.2741029077701832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}