{"id":"W1530666631","doi":"10.4049/jimmunol.0801485","title":"Bone Marrow-Derived Mast Cells Accumulate in the Central Nervous System During Inflammation but Are Dispensable for Experimental Autoimmune Encephalomyelitis Pathogenesis","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Calgary; University of British Columbia","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada; Michael Smith Health Research BC","keywords":"Experimental autoimmune encephalomyelitis; Mast cell; Bone marrow; Immunology; Encephalomyelitis; Biology; Central nervous system; Inflammation; Multiple sclerosis; Pathogenesis; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006698112,0.0002300945,0.0005068023,0.000146633,0.0003668482,0.00002871182,0.0005658008,0.0002037965,0.0001284706],"category_scores_gemma":[0.0000319938,0.0001432035,0.0001789011,0.00012567,0.0001880515,0.0001481094,0.00005817354,0.0003774587,0.00002813552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001584408,"about_ca_system_score_gemma":0.00004789191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001068383,"about_ca_topic_score_gemma":0.00002525231,"domain_scores_codex":[0.9978277,0.0005780839,0.0008253076,0.0001491424,0.00006745508,0.0005523107],"domain_scores_gemma":[0.9985715,0.0001867622,0.0007827306,0.0003364703,0.0001054492,0.00001708138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001343324,0.0001099465,0.00008361335,0.00002932765,0.0001001504,0.0000613712,0.002804146,0.0002213783,0.9931722,0.0002481217,0.00006423393,0.00176222],"study_design_scores_gemma":[0.004420131,0.000838819,0.2821462,0.0001856942,0.0001226126,0.002784297,0.01459829,0.0000395516,0.6924098,0.00005676217,0.002138093,0.0002597779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858461,0.01177214,0.0001408963,0.0008111965,0.0008500061,0.0004361563,0.0000224516,0.00001946541,0.0001016137],"genre_scores_gemma":[0.9989057,0.0003782574,0.00007453516,0.00005745976,0.0001153972,0.00001228063,0.00001655705,0.00001604619,0.0004238284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3007624,"threshold_uncertainty_score":0.583967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030041710823461,"score_gpt":0.2144751090543201,"score_spread":0.2041746919460855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}