{"id":"W1531449583","doi":"10.4049/jimmunol.175.3.1516","title":"CD8α+, but Not CD8α−, Dendritic Cells Tolerize Th2 Responses via Contact-Dependent and -Independent Mechanisms, and Reverse Airway Hyperresponsiveness, Th2, and Eosinophil Responses in a Mouse Model of Asthma","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Immunology; Eosinophil; CD8; Dendritic cell; Biology; T cell; Cytotoxic T cell; Immune system; Asthma; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000924154,0.0003917937,0.0001931229,0.0001096299,0.00009590742,0.0002184844,0.0001240308,0.0001846447,0.000791162],"category_scores_gemma":[0.00008899865,0.0001050274,0.0001264612,0.00006361063,0.0001941285,0.000151439,0.00008689881,0.0006113974,0.0004187414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001395719,"about_ca_system_score_gemma":0.0001077074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001118157,"about_ca_topic_score_gemma":0.0001978966,"domain_scores_codex":[0.9998847,0.00001809517,0.00001014762,0.00002203861,0.00002272879,0.00004219082],"domain_scores_gemma":[0.9999323,0.000006522173,0.00001890701,0.0000114999,0.000007994488,0.00002273889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001281161,0.00003918581,0.0002982665,0.0000199351,0.000002705405,0.00004012112,0.000004354552,0.00002783427,0.997771,0.00004047025,0.00004173481,0.001586287],"study_design_scores_gemma":[0.00008222306,0.0008363019,0.005069927,0.000009836079,0.00002706195,0.0008596629,0.00002185008,0.0009702123,0.9883194,0.0001224639,0.003678138,0.00000282777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955636,0.001146744,0.001599211,0.00008666333,0.00004597158,0.00001987937,0.00007651382,0.00005413548,0.001407256],"genre_scores_gemma":[0.9950383,0.0006409551,0.00102997,0.00007875483,0.00003299431,0.00001949988,0.000263905,0.00001354554,0.002882022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000791162,"threshold_uncertainty_score":0.002646685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314906201301096,"score_gpt":0.2283089422769955,"score_spread":0.2151598802639845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}