{"id":"W1531819701","doi":"10.1074/jbc.m011196200","title":"Decreased Expression of Specific Genes in Yeast Cells Lacking Histone H1","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Medical Research Council; Medical Research Council Canada; University of Toronto","keywords":"Histone H1; Biology; Chromatin; ChIP-on-chip; Histone H2A; Histone code; Nucleosome; Histone; Histone methylation; ChIA-PET; Histone methyltransferase; Histone H4; Chromatin immunoprecipitation; Chromatin remodeling; Genetics; Molecular biology; Gene; Gene expression; Promoter; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001217154,0.0006118582,0.0005487179,0.0002575562,0.0001812417,0.0005510293,0.0003007471,0.0004140259,0.001314983],"category_scores_gemma":[0.0001660396,0.0002713406,0.0004331458,0.0003032948,0.0003748801,0.0002141773,0.0003175146,0.0008207987,0.0007587434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003122143,"about_ca_system_score_gemma":0.0002468224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00105637,"about_ca_topic_score_gemma":0.0009426451,"domain_scores_codex":[0.9997827,0.00002017702,0.00002376178,0.00007164673,0.00005540983,0.00004631811],"domain_scores_gemma":[0.9997138,0.00006558684,0.00005711672,0.0000486551,0.00003598454,0.00007887206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000528556,0.000009028732,0.00007872293,0.00001730896,0.000002932232,0.00003393424,0.000007637255,0.00002798763,0.9994722,0.0000225488,0.00001535299,0.0002593543],"study_design_scores_gemma":[0.00001547852,0.0001348682,0.006030665,0.000006017115,0.00001976662,0.0001852115,0.00005146547,0.0006951664,0.99159,0.00005651412,0.001207596,0.000007412226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893261,0.001713101,0.004618989,0.0001513144,0.00006585431,0.00003080771,0.002777246,0.0002611159,0.001055455],"genre_scores_gemma":[0.9821609,0.00123604,0.004536035,0.0001553976,0.00001591062,0.00006975064,0.006102596,0.0001498076,0.005573614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001314983,"threshold_uncertainty_score":0.004399002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584349450574583,"score_gpt":0.2433758942760348,"score_spread":0.227532399770289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}