{"id":"W1531819701","doi":"10.1074/jbc.m011196200","title":"Decreased Expression of Specific Genes in Yeast Cells Lacking Histone H1","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Medical Research Council; Medical Research Council Canada; University of Toronto","keywords":"Histone H1; Biology; Chromatin; ChIP-on-chip; Histone H2A; Histone code; Nucleosome; Histone; Histone methylation; ChIA-PET; Histone methyltransferase; Histone H4; Chromatin immunoprecipitation; Chromatin remodeling; Genetics; Molecular biology; Gene; Gene expression; Promoter; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002011209,0.0001181019,0.0002307688,0.00001924972,0.00002218982,0.000008972951,0.0002355525,0.0002138144,0.00009416546],"category_scores_gemma":[0.00004388253,0.00009058828,0.0001351321,0.00006186023,0.00007794621,0.000002393223,0.00007495318,0.0001310545,9.129584e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002874036,"about_ca_system_score_gemma":0.0000414424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002544888,"about_ca_topic_score_gemma":8.962364e-7,"domain_scores_codex":[0.9991165,0.0000284477,0.0004469068,0.0001518577,0.00009977556,0.0001565302],"domain_scores_gemma":[0.9993095,0.0000137731,0.0003473106,0.0001606384,0.0000847445,0.00008400625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001626779,0.0001374494,0.005407992,0.00001669426,0.00000837323,0.00003020222,0.000008209002,0.0001430067,0.9930642,9.225514e-7,0.0002333469,0.0007869772],"study_design_scores_gemma":[0.0005693847,0.0001143495,0.002905152,0.00004639836,0.000004268415,0.0001113124,0.0000863738,0.00002634902,0.9904844,0.00006150381,0.005481183,0.00010937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966835,0.002061702,0.000325968,0.00001942931,0.00006420988,0.00003100122,0.000008943849,0.000001830688,0.0008034499],"genre_scores_gemma":[0.9956675,0.002292079,0.001648787,0.00002177224,0.0002222453,8.880227e-7,0.00001982016,0.000008329353,0.0001186218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005247836,"threshold_uncertainty_score":0.3694082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584349450574583,"score_gpt":0.2433758942760348,"score_spread":0.227532399770289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}