{"id":"W1532125617","doi":"10.1016/j.bpj.2015.06.057","title":"A Disulfide Bond Is Required for the Transmission of Forces through SUN-KASH Complexes","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Office of Science; National Science Foundation","keywords":"Cytoskeleton; Mechanosensitive channels; Biophysics; Mechanotransduction; Chemistry; Nucleus; Cell biology; Biology; Cell; Biochemistry; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008602267,0.00008541004,0.000113724,0.000008781298,0.0001052295,0.00002406961,0.0001393867,0.00006506856,0.000009341988],"category_scores_gemma":[0.00002218816,0.00004984626,0.0001610953,0.00004322206,0.00008921351,0.000007854162,0.00002371357,0.00006981621,0.000001727849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005944324,"about_ca_system_score_gemma":0.00003567992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007758654,"about_ca_topic_score_gemma":0.000001246406,"domain_scores_codex":[0.9994472,0.00001889806,0.0001572352,0.0001132761,0.0001356121,0.000127762],"domain_scores_gemma":[0.9995878,0.00001710351,0.00009269069,0.0001287262,0.0001058657,0.00006784384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004094157,0.00003196272,0.00003363049,0.000008362496,0.000052856,4.713851e-7,0.0002863273,0.0000081621,0.9699556,0.000412271,0.0238031,0.004997786],"study_design_scores_gemma":[0.001053472,0.0009242813,0.0005798173,0.00001635141,0.00006738673,0.00004393191,0.0003479382,0.0002680141,0.7329234,0.003682876,0.2599738,0.0001187843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9482611,0.0005081416,0.04845411,0.001659059,0.0003800268,0.0001903634,0.00003309357,0.000006574162,0.0005075398],"genre_scores_gemma":[0.9963599,0.00008968265,0.002152503,0.0003114723,0.0008847318,0.00000277924,0.00001306295,0.0000129342,0.0001729508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2370322,"threshold_uncertainty_score":0.2032671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02730400117850488,"score_gpt":0.2822510723382035,"score_spread":0.2549470711596986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}