{"id":"W1532269447","doi":"10.1093/annonc/mdu349.91","title":"The Relationship Between Egfr and Kras Mutation Status and Overall Survival (Os) in the Ncic Ctg Br.26 Randomized Trial of Dacomitinib (D) Versus Placebo (P) in Patients with Previously Treated Non Small Cell Lung Cancer (Nsclc)","year":2014,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; BC Cancer Agency; Princess Margaret Cancer Centre; Queen's University; University Health Network; Juravinski Cancer Centre","funders":"","keywords":"Medicine; KRAS; Internal medicine; Oncology; Placebo; Randomized controlled trial; Cancer; Pathology; Colorectal cancer; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001654808,0.001122683,0.001868237,0.0003105403,0.0003214914,0.00100361,0.0008411282,0.001192482,0.003173717],"category_scores_gemma":[0.002048889,0.0005451147,0.001525762,0.0003444985,0.001028486,0.0007108949,0.000390382,0.003197652,0.0004064636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008105221,"about_ca_system_score_gemma":0.0008038174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001998249,"about_ca_topic_score_gemma":0.004582719,"domain_scores_codex":[0.9992544,0.0004834256,0.00003888197,0.00009979914,0.00004092118,0.00008252874],"domain_scores_gemma":[0.9989806,0.0003620292,0.0001964446,0.00007795366,0.00003862388,0.0003443327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9836566,0.001428689,0.002485326,0.0001909951,0.001055262,0.00002587156,0.00001705647,0.0003844298,0.001991653,0.00005891088,0.0005888617,0.008116324],"study_design_scores_gemma":[0.8856099,0.09057259,0.01769095,0.00005352345,0.002602174,0.00008031059,0.00003765029,0.001304839,0.0008013356,0.0002336986,0.0009812707,0.00003179526],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920167,0.004130541,0.0001958026,0.0007224225,0.0003654483,0.00034788,0.0006447106,0.0000362618,0.0015403],"genre_scores_gemma":[0.9961493,0.0009848976,0.0002653984,0.0004535561,0.0002543288,0.0002133083,0.0005905808,0.000009303296,0.001079305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003173717,"threshold_uncertainty_score":0.01061714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04690554964151951,"score_gpt":0.3791627575029277,"score_spread":0.3322572078614082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}