{"id":"W1533300735","doi":"10.1111/j.1360-0443.2012.04036.x","title":"<scp>M</scp>aternal <scp>O</scp>pioid <scp>T</scp>reatment: <scp>H</scp>uman <scp>E</scp>xperimental <scp>R</scp>esearch (<scp>MOTHER</scp>)—approach, issues and lessons learned","year":2012,"lang":"en","type":"review","venue":"Addiction","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"National Center for Research Resources; National Institute on Drug Abuse; Government of Ontario; Brown University","keywords":"Attrition; Clinical trial; Randomized controlled trial; Protocol (science); Focus group; Medicine; Methadone; Random assignment; Psychology; Pharmacology; Alternative medicine; Marketing; Business","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01718693,0.0003230223,0.0006183049,0.0006137883,0.0007418978,0.001809527,0.001662809,0.001484941,0.0881798],"category_scores_gemma":[0.03190267,0.000226941,0.0004054248,0.0007565265,0.00186144,0.0009780006,0.002014546,0.001847926,0.02003509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002127545,"about_ca_system_score_gemma":0.01091076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007566144,"about_ca_topic_score_gemma":0.01307888,"domain_scores_codex":[0.9936253,0.00355822,0.000506455,0.0004375446,0.001580967,0.0002914509],"domain_scores_gemma":[0.9711152,0.01133594,0.001559549,0.00313657,0.008867525,0.003985065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002590881,0.0005576795,0.003844933,0.002160142,0.0000608819,0.000772469,0.000718091,0.00065793,0.004279131,0.01538938,0.5359427,0.4330257],"study_design_scores_gemma":[0.001855308,0.002432637,0.01545995,0.00333662,0.00007696176,0.001136701,0.001329592,0.002230236,0.006663704,0.009695294,0.9557172,0.00006596425],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.04807557,0.02210137,0.05133884,0.402893,0.02084441,0.01806544,0.01254508,0.002763457,0.4213729],"genre_scores_gemma":[0.3431878,0.03212464,0.113595,0.08647795,0.0092098,0.02514033,0.006372729,0.002391927,0.3814998],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0881798,"threshold_uncertainty_score":0.2949908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06105814040052462,"score_gpt":0.3463032350675578,"score_spread":0.2852450946670332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}