{"id":"W1533511335","doi":"10.1002/0471267295.ch5","title":"Irreversible Enzyme Inhibition","year":2002,"lang":"en","type":"other","venue":"","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Enzyme inhibition; Simple (philosophy); Substrate (aquarium); Enzyme; Chemistry; Biophysics; Biochemistry; Biology; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003900907,0.001351182,0.001034219,0.000446205,0.0004858417,0.001465213,0.001981175,0.001123535,0.007633998],"category_scores_gemma":[0.000564068,0.0004441075,0.0008116578,0.0004352783,0.001037446,0.001748846,0.001081173,0.00219449,0.003338828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001404581,"about_ca_system_score_gemma":0.0005092237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006652723,"about_ca_topic_score_gemma":0.0007098124,"domain_scores_codex":[0.9993116,0.00004763064,0.00002587175,0.000175574,0.0003631608,0.00007615059],"domain_scores_gemma":[0.999803,0.00006944724,0.00003540168,0.00003920358,0.00003721691,0.00001581854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111524,0.0001882565,0.0003278278,0.002267963,0.00007218369,0.0004382586,0.0002409736,0.02415048,0.1690093,0.6928056,0.01524233,0.09514528],"study_design_scores_gemma":[0.00004196389,0.0002315091,0.0004264563,0.0002766278,0.00007393937,0.001593387,0.00006938433,0.08381258,0.4363152,0.1513688,0.3256685,0.0001215917],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.04269636,0.05952067,0.5726348,0.001997875,0.002756878,0.0004022212,0.0007400404,0.001858732,0.3173924],"genre_scores_gemma":[0.524436,0.05902675,0.05497714,0.001675744,0.0004290745,0.000530115,0.001131406,0.0004204487,0.3573734],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007633998,"threshold_uncertainty_score":0.02553821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009344247376409823,"score_gpt":0.2208327314323753,"score_spread":0.2114884840559655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}