{"id":"W1533511335","doi":"10.1002/0471267295.ch5","title":"Irreversible Enzyme Inhibition","year":2002,"lang":"en","type":"other","venue":"","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Enzyme inhibition; Simple (philosophy); Substrate (aquarium); Enzyme; Chemistry; Biophysics; Biochemistry; Biology; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003020854,0.0001364268,0.0001083369,0.00007285031,0.00001677003,0.00001208208,0.00006139874,0.000305533,0.006979953],"category_scores_gemma":[0.00001255616,0.0001261633,0.00007870243,0.00006558873,0.00002414731,8.42799e-7,0.0000431424,0.00004093496,0.0003885691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006387961,"about_ca_system_score_gemma":0.0000112926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002272376,"about_ca_topic_score_gemma":0.00005255221,"domain_scores_codex":[0.9994327,0.00001543237,0.00009317556,0.0002742548,0.00007547741,0.0001089567],"domain_scores_gemma":[0.9995776,9.499209e-7,0.00006897039,0.0002975511,0.00002035374,0.00003453742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001318748,0.00002381112,0.000008323264,0.00001522501,0.0000226888,6.01466e-7,0.000001594158,0.000002667291,0.04316481,0.00004442203,0.9564558,0.0002587193],"study_design_scores_gemma":[0.0001394748,0.00003829834,0.000002444426,0.00002021782,0.00001705287,0.000002420252,0.000005491379,0.000009888713,0.107834,0.000003184817,0.8917746,0.0001529149],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0001173727,0.002213219,0.002852066,0.00002871969,0.0001410925,0.0001272471,0.00002615091,0.00004528529,0.9944488],"genre_scores_gemma":[0.00222005,0.001067752,0.000312827,0.0002192017,0.0004447333,0.0000105073,0.001729526,0.0001827033,0.9938127],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.06468122,"threshold_uncertainty_score":0.9939278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009344247376409823,"score_gpt":0.2208327314323753,"score_spread":0.2114884840559655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}