{"id":"W1533670919","doi":"10.1002/bdra.23320","title":"Epigenetic mechanism causes Wnt9b deficiency and nonsyndromic cleft lip and palate in the A/WySn mouse strain","year":2014,"lang":"en","type":"article","venue":"Birth Defects Research Part A Clinical and Molecular Teratology","topic":"Cleft Lip and Palate Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; McGill University","keywords":"Retrotransposon; DNA methylation; Methylation; Embryo; Biology; Gene; Epigenetics; Genetics; Mutant; Transcription (linguistics); Coding region; Molecular biology; Allele; Transposable element; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904179,0.0006235797,0.000288216,0.0008750136,0.0002790499,0.0002550585,0.0002905265,0.0005905838,0.003408214],"category_scores_gemma":[0.0001741503,0.0003951319,0.0004448869,0.0002774434,0.0003908497,0.0001775889,0.0004090928,0.000717354,0.0007519531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002559269,"about_ca_system_score_gemma":0.0002820007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442188,"about_ca_topic_score_gemma":0.002976807,"domain_scores_codex":[0.9997037,0.00002790441,0.00005230222,0.00009326476,0.00008310525,0.00003969324],"domain_scores_gemma":[0.9996685,0.00002949816,0.0001697188,0.00002944044,0.00002420116,0.00007876002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001686593,0.00005698676,0.001121701,0.00003209803,0.00001458357,0.0004676137,0.00002332695,0.00003865792,0.9970444,0.0001786781,0.00007985647,0.0007733126],"study_design_scores_gemma":[0.0002197451,0.001064449,0.08686553,0.00009905981,0.0001948498,0.009021246,0.0002460163,0.002080228,0.8941402,0.000381048,0.005654649,0.00003298593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938403,0.0006659355,0.002905987,0.0001001088,0.0000292626,0.00004440084,0.001266821,0.0001173748,0.001029867],"genre_scores_gemma":[0.9854369,0.0009518531,0.003638386,0.000141804,0.00001764713,0.00014673,0.001914945,0.0001136474,0.007638284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003408214,"threshold_uncertainty_score":0.01140165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05294864562200374,"score_gpt":0.3759069385964297,"score_spread":0.322958292974426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}