{"id":"W153383899","doi":"10.1023/a:1008306727354","title":"Letter to the Editor: Sequence-specific resonance assignments and partial unfolding of extracellular domains II and III of E-cadherin","year":2000,"lang":"en","type":"letter","venue":"Journal of Biomolecular NMR","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Chemistry; Extracellular; Sequence (biology); Cadherin; Resonance (particle physics); Biophysics; Computational biology; Nuclear magnetic resonance; Biochemistry; Physics; Atomic physics; Cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005187741,0.0002964443,0.0004600368,0.0001205539,0.00009929355,0.0000338791,0.0004106598,0.0004941327,0.00004100539],"category_scores_gemma":[0.00002238666,0.0002250352,0.0001815416,0.0001312004,0.0002465855,0.000009266553,0.0001698712,0.0004801044,9.906552e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003052161,"about_ca_system_score_gemma":0.0001195009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006996323,"about_ca_topic_score_gemma":7.248289e-7,"domain_scores_codex":[0.9979085,0.000136325,0.0007576575,0.0003368916,0.0005598638,0.0003007984],"domain_scores_gemma":[0.9987721,0.00002333475,0.0006452561,0.0003274012,0.0001507022,0.00008123811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001276358,0.0000162731,0.00004197323,0.00003555082,0.0001349463,0.00008601965,0.0001228201,0.00001272298,0.5561144,0.000001845102,0.4415398,0.001766001],"study_design_scores_gemma":[0.0004846446,0.0003069836,0.00002828173,0.0001900051,0.00005496986,0.00007037872,0.0000118487,0.00000313473,0.2944121,0.00001345347,0.7042425,0.0001816862],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8279279,0.07767656,0.008430363,0.08110967,0.003641626,0.0008066879,0.0001579682,0.000009032534,0.0002401729],"genre_scores_gemma":[0.8390536,0.01460131,0.006179797,0.09053695,0.04548572,0.00004473085,0.0001583342,0.0002484273,0.003691156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2627027,"threshold_uncertainty_score":0.9176669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01501891382687035,"score_gpt":0.2425411935726963,"score_spread":0.227522279745826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}