{"id":"W1534658079","doi":"10.4049/jimmunol.173.2.932","title":"Adenosine Acts through A2 Receptors to Inhibit IL-2-Induced Tyrosine Phosphorylation of STAT5 in T Lymphocytes: Role of Cyclic Adenosine 3′,5′-Monophosphate and Phosphatases","year":2004,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council; Faculty of Medicine, Dalhousie University; Dalhousie University; Nova Scotia Health Research Foundation","keywords":"Protein tyrosine phosphatase; Adenosine; Phosphorylation; Tyrosine phosphorylation; Forskolin; Adenosine A2B receptor; Adenylyl cyclase; Biology; Receptor tyrosine kinase; Tyrosine kinase; Chemistry; Cell biology; Adenosine receptor; Signal transduction; Molecular biology; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004180166,0.0002078421,0.0004442283,0.000128429,0.00005094588,0.000007555564,0.0003072905,0.0001756852,0.00002287234],"category_scores_gemma":[0.0002132646,0.0001604217,0.00007983112,0.00031965,0.0001632266,0.0000285202,0.0001505828,0.0001819763,0.000002072947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000055323,"about_ca_system_score_gemma":0.0001915489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000342379,"about_ca_topic_score_gemma":0.00001796411,"domain_scores_codex":[0.9984712,0.0001147834,0.0008017328,0.0001780121,0.0001690965,0.0002651507],"domain_scores_gemma":[0.998705,0.00007129038,0.0006563527,0.0002861632,0.0002261809,0.00005504833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001971239,0.0001866127,0.0008494378,0.0000200538,0.0001472734,0.000006381468,0.001178646,0.001919305,0.9918302,0.0001716543,0.0002650189,0.001454148],"study_design_scores_gemma":[0.002483124,0.002017737,0.004098295,0.0001911505,0.0000654634,0.0001336273,0.0008500157,0.000003663732,0.9875379,0.0005328701,0.001934622,0.0001515018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9332296,0.06567321,0.0002842896,0.0004232342,0.0001610881,0.0001676032,0.00002181887,0.000003190793,0.00003595417],"genre_scores_gemma":[0.9916111,0.007263748,0.0008123881,0.0001480287,0.00009044579,0.000003079016,0.00002388011,0.00002503572,0.00002234746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05840946,"threshold_uncertainty_score":0.6541809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009563038552825507,"score_gpt":0.24127022297217,"score_spread":0.2317071844193445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}