{"id":"W1535825129","doi":"10.1002/9780470514344.ch11","title":"Roles of Secondary Metabolites from Microbes","year":2007,"lang":"en","type":"review","venue":"Novartis Foundation symposium","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Secondary metabolism; Biology; Gene; Horizontal gene transfer; Organism; Polyketide; Phylogenetics; Secondary metabolite; Multicellular organism; Model organism; Mechanism (biology); Genetics; Biosynthesis; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003972184,0.0004414879,0.00202914,0.0004151041,0.0000650851,0.00005299562,0.0002045186,0.0004569369,0.002304321],"category_scores_gemma":[0.0001144617,0.0003214249,0.0005932451,0.0005166199,0.0001386396,0.0001425002,0.00008619342,0.0004451132,0.0004294179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009202748,"about_ca_system_score_gemma":0.0004035454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001107241,"about_ca_topic_score_gemma":0.00002960697,"domain_scores_codex":[0.9975737,0.00009768312,0.001166445,0.0005841599,0.0002943026,0.0002836509],"domain_scores_gemma":[0.9980982,0.0002093462,0.000677632,0.0005908604,0.000318002,0.0001059798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000336431,0.0001040687,0.000005372405,0.00566833,0.0004392234,0.000006972459,0.00005366723,1.282479e-8,0.04369969,0.000121757,0.001344865,0.9485224],"study_design_scores_gemma":[0.0002569348,0.00005264523,0.0000158171,0.004661696,0.002067083,0.00004744366,0.000009263376,2.32586e-7,0.04126082,0.00002756358,0.9513223,0.0002781642],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003495558,0.9954566,0.00003516718,0.000274696,0.0006268817,0.000756873,0.0002832467,0.00006167573,0.002155273],"genre_scores_gemma":[0.0003138818,0.9928346,0.002021589,0.0001778293,0.0009552978,0.000003376715,0.001971076,0.0000662372,0.001656057],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9499775,"threshold_uncertainty_score":0.9999238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04294655018090122,"score_gpt":0.3289140711447347,"score_spread":0.2859675209638335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}