{"id":"W1535825129","doi":"10.1002/9780470514344.ch11","title":"Roles of Secondary Metabolites from Microbes","year":2007,"lang":"en","type":"review","venue":"Novartis Foundation symposium","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Secondary metabolism; Biology; Gene; Horizontal gene transfer; Organism; Polyketide; Phylogenetics; Secondary metabolite; Multicellular organism; Model organism; Mechanism (biology); Genetics; Biosynthesis; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005260216,0.0009663298,0.001291001,0.002130581,0.0003737288,0.001518911,0.0007086992,0.001183759,0.003015983],"category_scores_gemma":[0.0004654657,0.0003185715,0.0004246376,0.001601897,0.0006449712,0.001807539,0.00095489,0.001490495,0.00269681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005746205,"about_ca_system_score_gemma":0.0007280633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000444977,"about_ca_topic_score_gemma":0.0006969865,"domain_scores_codex":[0.9997787,0.00003978855,0.00002723236,0.00003965032,0.00009195707,0.00002270714],"domain_scores_gemma":[0.9997913,0.00007615133,0.00003920215,0.00001011416,0.00004875493,0.00003446938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001089534,0.00006531044,0.0002409269,0.01317874,0.00007776953,0.0007548303,0.0001058195,0.0003522851,0.01252959,0.005273582,0.01488676,0.9524254],"study_design_scores_gemma":[0.00001635943,0.00009482775,0.0007637881,0.00146082,0.0000443094,0.002525067,0.00005029362,0.00005052264,0.002126154,0.002257076,0.9905949,0.00001586066],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001746283,0.9980332,0.0001358448,0.0001420983,0.0001603276,0.000004390989,0.00001089006,0.000006041654,0.001332552],"genre_scores_gemma":[0.001553937,0.9970363,0.0002321063,0.0001727131,0.000213388,0.000007594855,0.00003484666,0.00000141314,0.0007477072],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003015983,"threshold_uncertainty_score":0.01008952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04294655018090122,"score_gpt":0.3289140711447347,"score_spread":0.2859675209638335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}