{"id":"W1535956128","doi":"10.1186/1471-2121-5-4","title":"Protein kinase Cζ regulates phospholipase D activity in rat-1 fibroblasts expressing the α1A adrenergic receptor","year":2004,"lang":"en","type":"article","venue":"BMC Cell Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; U.S. Public Health Service; University of South Florida; American Heart Association","keywords":"Protein kinase C; Phospholipase D; Biology; Bisindolylmaleimide; Rottlerin; Cell biology; Receptor; Stimulation; Endocrinology; Enzyme activator; Internal medicine; Signal transduction; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003102633,0.0002514083,0.0002074357,0.00006564662,0.0001508598,0.00003047858,0.0002516864,0.0003116848,0.00005384021],"category_scores_gemma":[0.00008581075,0.0001932284,0.0001226169,0.00017864,0.0002061541,0.00000832327,0.0001634192,0.0001748485,0.00002552566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004641982,"about_ca_system_score_gemma":0.0001634973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001199349,"about_ca_topic_score_gemma":0.0001300122,"domain_scores_codex":[0.9984434,0.0002548058,0.0002657059,0.0005363971,0.00008460042,0.0004150691],"domain_scores_gemma":[0.9991902,0.0000239577,0.0001594395,0.0004883239,0.0000476024,0.00009047356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000267498,0.0001053288,0.0003707336,0.00003035296,0.000006757663,0.000003727115,0.00003796028,0.002656916,0.9942219,0.0002317201,0.00004471249,0.002022366],"study_design_scores_gemma":[0.001336061,0.0001621539,0.000584626,0.00005955112,0.000005703412,0.000004970932,0.00003211305,0.000106249,0.989681,0.0004648003,0.007305088,0.0002576759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950449,0.001670029,0.00209791,0.0001618568,0.0001238253,0.000536889,0.00001382587,0.00002735426,0.0003233473],"genre_scores_gemma":[0.9966662,0.00004064628,0.002282306,0.00009548486,0.0002097012,0.0001333219,0.0001208534,0.00002742311,0.000424055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007260376,"threshold_uncertainty_score":0.7879625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01196609874370446,"score_gpt":0.2362231050746159,"score_spread":0.2242570063309114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}