{"id":"W1536557591","doi":"10.1046/j.1365-2958.2003.t01-1-03329.x","title":"Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the <i>Escherichia coli</i> sequestration mutant <i>seqA2</i>","year":2003,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nexen (Canada)","funders":"Norges Forskningsråd; Kreftforeningen","keywords":"SeqA protein domain; Biology; Mutant; Escherichia coli; DNA; Cell biology; Nucleoid; Mutation; Genetics; Gene; DNA replication; Origin of replication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001294103,0.0005654948,0.0003028339,0.0002441392,0.0001748887,0.000432202,0.0003137385,0.0003887604,0.001182576],"category_scores_gemma":[0.0002728722,0.0003601669,0.000342872,0.0001512968,0.0002847413,0.000213025,0.0004026965,0.0006543632,0.0006292454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003610646,"about_ca_system_score_gemma":0.0003393343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001709027,"about_ca_topic_score_gemma":0.001841211,"domain_scores_codex":[0.9997905,0.00001958728,0.00002556832,0.00005373969,0.00008315852,0.00002740463],"domain_scores_gemma":[0.9995357,0.00007298725,0.0001205771,0.00008970935,0.00005040168,0.0001306518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001922797,0.000008945539,0.0001964889,0.00001324781,0.000004129291,0.00003593906,0.000006303242,0.00003061066,0.9993411,0.00004156428,0.00001380272,0.0002886388],"study_design_scores_gemma":[0.000004483141,0.00006355227,0.004522901,0.000003003845,0.000008074704,0.0005840283,0.00001821465,0.0006365548,0.993353,0.00003546799,0.0007654215,0.000005284143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930158,0.0004419234,0.005008016,0.0000743869,0.00002333021,0.00001937712,0.0005230996,0.0001392953,0.0007547677],"genre_scores_gemma":[0.9931608,0.0001538663,0.002698134,0.00004477064,0.000004537903,0.00003270271,0.001076945,0.00008834466,0.002739866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001709027,"threshold_uncertainty_score":0.003956139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213389975207436,"score_gpt":0.2171445452432301,"score_spread":0.2050106454911557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}