{"id":"W1538131766","doi":"10.1111/j.1747-4949.2012.00896.x","title":"NeuroThera® Efficacy and Safety Trial – 3 (NEST-3): A Double-Blind, Randomized, Sham-Controlled, Parallel Group, Multicenter, Pivotal Study to Assess the Safety and Efficacy of Transcranial Laser Therapy with the NeuroThera® Laser System for the Treatment of Acute Ischemic Stroke within 24 h of Stroke Onset","year":2012,"lang":"en","type":"article","venue":"International Journal of Stroke","topic":"Laser Applications in Dentistry and Medicine","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Randomized controlled trial; Clinical trial; Transcranial Doppler; Stroke (engine); Clinical endpoint; Population; Randomization; Physical therapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005420068,0.002417238,0.003423828,0.0005463707,0.0008690535,0.001227509,0.001414072,0.002943981,0.007867516],"category_scores_gemma":[0.00338789,0.0008137085,0.001841695,0.0004322281,0.002207565,0.001615171,0.0005406136,0.003076861,0.0016738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006273845,"about_ca_system_score_gemma":0.002596491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000401509,"about_ca_topic_score_gemma":0.001097718,"domain_scores_codex":[0.9980933,0.001099139,0.0001307714,0.000287283,0.0002301718,0.0001592468],"domain_scores_gemma":[0.9976083,0.0004895901,0.0007159697,0.0002552754,0.0002369094,0.0006940075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9786274,0.01072161,0.0007039137,0.0005136643,0.0003248809,0.00004508118,0.00004547733,0.0001078562,0.002923345,0.00018572,0.0009469336,0.004854122],"study_design_scores_gemma":[0.9532527,0.04484115,0.000749049,0.00001615076,0.0001177068,0.00002605009,0.000006411035,0.000133006,0.0003048384,0.00009763228,0.0004448454,0.00001029489],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9317977,0.004208543,0.002350646,0.001466307,0.00116301,0.05102643,0.003388377,0.0003127516,0.00428624],"genre_scores_gemma":[0.8782359,0.003228402,0.01073327,0.005100202,0.002433539,0.08743702,0.004123468,0.0001072347,0.008601045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007867516,"threshold_uncertainty_score":0.02866441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03286619579994592,"score_gpt":0.3309958696630902,"score_spread":0.2981296738631443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}