{"id":"W1538131766","doi":"10.1111/j.1747-4949.2012.00896.x","title":"NeuroThera® Efficacy and Safety Trial – 3 (NEST-3): A Double-Blind, Randomized, Sham-Controlled, Parallel Group, Multicenter, Pivotal Study to Assess the Safety and Efficacy of Transcranial Laser Therapy with the NeuroThera® Laser System for the Treatment of Acute Ischemic Stroke within 24 h of Stroke Onset","year":2012,"lang":"en","type":"article","venue":"International Journal of Stroke","topic":"Laser Applications in Dentistry and Medicine","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Randomized controlled trial; Clinical trial; Transcranial Doppler; Stroke (engine); Clinical endpoint; Population; Randomization; Physical therapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001841036,0.0003275982,0.001223521,0.0001467069,0.0001289614,0.00003871229,0.0004599247,0.0000678687,0.00002153781],"category_scores_gemma":[0.00008488179,0.0001383877,0.0004329739,0.0001073833,0.0003753292,0.000132913,0.00002789596,0.0002887684,3.285919e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006516816,"about_ca_system_score_gemma":0.0001119735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006216822,"about_ca_topic_score_gemma":0.00002625445,"domain_scores_codex":[0.9968838,0.0003533309,0.001389799,0.0002352974,0.0009067715,0.0002310056],"domain_scores_gemma":[0.9950104,0.002799897,0.001146787,0.0003900587,0.0005007584,0.0001521285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9723115,0.004324089,0.0021227,0.0000326315,0.007203618,0.00001537144,0.00368507,0.0003159989,0.008335372,0.00007986136,0.00003195441,0.001541851],"study_design_scores_gemma":[0.9718102,0.007606481,0.005415321,0.000170624,0.003188087,0.0003768565,0.0023181,0.0002902856,0.007678635,8.097721e-7,0.001024164,0.0001204774],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982509,0.0005309798,0.003883784,0.002433526,0.0006977889,0.00950332,0.0003811799,0.000008499052,0.00005199069],"genre_scores_gemma":[0.9973972,0.0006841814,0.0003156079,0.0001427881,0.0007154724,0.0003407592,0.00001230143,0.00003604864,0.0003556214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01488829,"threshold_uncertainty_score":0.5643288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03286619579994592,"score_gpt":0.3309958696630902,"score_spread":0.2981296738631443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}